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开发一种用于气管支架置入的创新介入方法。

Developing an innovative interventional approach for stenting trachea.

作者信息

Mazraehei Farahani Maryam, Kajbafzadeh Abdol-Mohammad, Kiani Arda, Kazemizadeh Hossein, Baghani Mostafa

机构信息

Farhikhtegan Medical Convergence Sciences Research Center, Farhikhtegan Hospital Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

Department of Pulmonary Medicine, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

BMJ Surg Interv Health Technol. 2025 May 8;7(1):e000180. doi: 10.1136/bmjsit-2022-000180. eCollection 2025.

Abstract

OBJECTIVES

Stenting is a method of controlling airway occlusions (CAO) that can be used alone or in combination with other treatments. There are different types of airway stents. One of the most widely used types is silicone stent. These stents are flexible and firm enough cylinders inserted into the airway by a rigid scope to relieve dyspnoea caused by CAO in malignant and non-malignant diseases. We have developed a method that can be applied quickly in remote urgent cases without a rigid scope.

DESIGN

We used two endotracheal tubes with a size of 8.5 for stenting.

SETTING

This research was conducted at Pediatric Urology and Regenerative Medicine Research Center, Children's Medical Center, Pediatric Center of Excellence, Animal Lab Tehran University of Medical Sciences, Tehran, Iran (IR).

PARTICIPANTS INSTEAD OF PATIENTS OR SUBJECTS

Two certified mature sheep (ewes).

INTERVENTIONS

Silicone stent placement for 2 months.

MAIN OUTCOME MEASURES

A method with minimal facilities for stenting without limitation of trachea size.

RESULTS

A pilot animal study has been performed on two mature certified sheep to test a stenting procedure. Stenting procedures have been successfully implemented on the animals' trachea.

CONCLUSIONS

We have developed a new simple, fast and cheap procedure for stenting silicon stents with minimum risk. We can easily place and rotate the stent during the procedure.

摘要

目的

支架置入是一种控制气道阻塞(CAO)的方法,可单独使用或与其他治疗方法联合使用。气道支架有不同类型。最广泛使用的类型之一是硅胶支架。这些支架是足够柔韧且坚固的圆柱体,通过硬质内镜插入气道,以缓解恶性和非恶性疾病中CAO引起的呼吸困难。我们开发了一种无需硬质内镜即可在远程紧急情况下快速应用的方法。

设计

我们使用两根8.5号气管内导管进行支架置入。

地点

本研究在伊朗德黑兰医科大学儿童医学中心儿科泌尿外科和再生医学研究中心、卓越儿科中心、动物实验室进行(IR)。

参与者而非患者或受试者

两只经认证的成年绵羊(母羊)。

干预措施

放置硅胶支架2个月。

主要观察指标

一种设施最少、不受气管尺寸限制的支架置入方法。

结果

对两只成年经认证的绵羊进行了一项试点动物研究,以测试一种支架置入程序。已在动物气管上成功实施了支架置入程序。

结论

我们开发了一种新的简单、快速且廉价的程序,用于置入硅胶支架,风险最小。在操作过程中,我们可以轻松放置和旋转支架。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1abd/12086876/306b488034f7/bmjsit-7-1-g001.jpg

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