用顺式二氯二氨铂（II）治疗的患者中铂的胆汁排泄情况。
Biliary excretion of platinum in a patient treated with cis-dichlorodiammineplatinum (II).
作者信息
Shelley M D, Fish R G, Adams M
出版信息
Antimicrob Agents Chemother. 1985 Feb;27(2):275-6. doi: 10.1128/AAC.27.2.275.
Abstract
Biliary excretion of platinum was measured in a patient receiving an intravenous infusion of cis-dichlorodiammineplatinum (II). Over a 3-day period, less than 1% of the administered platinum was detected in the bile, and 47% appeared in the urine, indicating that biliary excretion is a minor route of elimination.
摘要
对一名接受静脉输注顺二氯二氨铂（II）的患者的铂胆汁排泄情况进行了测定。在3天的时间里，胆汁中检测到的铂不到给药量的1%，而47%出现在尿液中，这表明胆汁排泄是一条次要的消除途径。
相似文献
1
Biliary excretion of platinum in a patient treated with cis-dichlorodiammineplatinum (II).用顺式二氯二氨铂（II）治疗的患者中铂的胆汁排泄情况。
Antimicrob Agents Chemother. 1985 Feb;27(2):275-6. doi: 10.1128/AAC.27.2.275.
2
Platinum concentrations in bile and plasma following rapid and 6-hour infusions of cis-dichlorodiammineplatinum(II).快速输注和顺式二氯二氨铂（II）6小时输注后胆汁和血浆中的铂浓度。
Cancer Treat Rep. 1979 Nov-Dec;63(11-12):2023-5.
3
Effect of a forced diuresis on the distribution and excretion (via urine and bile) of 195mplatinum when given as 195mplatinum cis-dichlorodiammineplatinum(II).
Cancer Treat Rep. 1979 Jun;63(6):951-60.
4
[Pharmacokinetics of cis-dichlorodiammineplatinum (II)].
Gan To Kagaku Ryoho. 1982 Apr;9(4):632-7.
5
[Excretion of cis-diamminedichloro platinum (CDDP) into pancreatic juice and hepatic bile].顺二氨二氯铂（CDDP）向胰液和肝胆汁中的排泄
Gan To Kagaku Ryoho. 1986 Oct;13(11):3180-5.
6
Pharmacokinetic evidence for an enterohepatic circulation in a patient treated with cis-dichlorodiammineplatinum (II).顺二氯二氨铂（II）治疗患者肝肠循环的药代动力学证据。
Res Commun Chem Pathol Pharmacol. 1980 May;28(2):319-28.
7
Biliary excretion of platinum in rats after administration of cisplatin and aqua(1,1-bis(aminomethyl)-cyclohexane)sulfatoplatinum(II) (spiroplatin, TNO-6).顺铂和水合（1,1-双（氨甲基）-环己烷）硫酸铂（II）（螺铂，TNO-6）给药后大鼠体内铂的胆汁排泄情况。
Cancer Lett. 1985 Aug;28(1):103-9. doi: 10.1016/0304-3835(85)90098-9.
8
Dithiocarbamate-induced biliary platinum excretion and the control of cis-platinum nephrotoxicity.二硫代氨基甲酸盐诱导的胆汁铂排泄与顺铂肾毒性的控制
Toxicol Appl Pharmacol. 1989 Feb;97(2):279-88. doi: 10.1016/0041-008x(89)90333-5.
9
Kinetics of cis-dichlorodiammineplatinum.
Clin Pharmacol Ther. 1979 Mar;25(3):351-7. doi: 10.1002/cpt1979253351.
10
Model independent pharmacokinetic study of cis-dichlorodiammineplatinum (II).
Int J Clin Pharmacol Ther Toxicol. 1985 Aug;23(8):430-3.
引用本文的文献
1
Pharmacokinetics of anticancer drugs in children.儿童抗癌药物的药代动力学
Clin Pharmacokinet. 1987 Mar;12(3):168-213. doi: 10.2165/00003088-198712030-00002.
本文引用的文献
1
Total body clearance and platinum accumulation in patients treated with cis-dichlorodiammine platinum (II).接受顺二氯二氨铂（II）治疗的患者的全身清除率和铂蓄积情况。
Ther Drug Monit. 1984;6(2):251-2. doi: 10.1097/00007691-198406000-00021.
2
Pharmacokinetics of free and total platinum species after short-term infusion of cisplatin.短期输注顺铂后游离铂和总铂物种的药代动力学。
Cancer Treat Rep. 1984 Mar;68(3):505-13.
3
Pharmacokinetics and protein binding of cis-dichlorodiammine platinum (II) administered as a one hour or as a twenty hour infusion.
Cancer Chemother Pharmacol. 1980;5(1):21-6. doi: 10.1007/BF00578558.
4
Platinum concentrations in bile and plasma following rapid and 6-hour infusions of cis-dichlorodiammineplatinum(II).快速输注和顺式二氯二氨铂（II）6小时输注后胆汁和血浆中的铂浓度。
Cancer Treat Rep. 1979 Nov-Dec;63(11-12):2023-5.
5
Effect of a forced diuresis on the distribution and excretion (via urine and bile) of 195mplatinum when given as 195mplatinum cis-dichlorodiammineplatinum(II).
Cancer Treat Rep. 1979 Jun;63(6):951-60.
6
Biliary excretion of drugs in man.人体中药物的胆汁排泄。
Clin Pharmacokinet. 1979 Sep-Oct;4(5):368-79. doi: 10.2165/00003088-197904050-00003.
Zotero 插件