阿苯达唑对人体蛔虫病、钩虫病和鞭虫病的杀卵作用。

Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis.

作者信息

Maisonneuve H, Rossignol J F, Addo A, Mojon M

出版信息

Ann Trop Med Parasitol. 1985 Feb;79(1):79-82. doi: 10.1080/00034983.1985.11811890.

DOI:10.1080/00034983.1985.11811890

Abstract

Albendazole, a broad spectrum anthelmintic, was administered as a 400 mg single dose to 20 patients harbouring Ascaris (ten cases), hookworms (four cases each of Ancylostoma duodenale and Necator americanus) and trichuriasis (ten cases). Faeces were obtained before treatment and during the following five days. Coprocultures were made for 90 days for Ascaris and Trichuris eggs, hookworm eggs were cultured by the Harada-Mori technique for at least eight days. Albendazole was ovicidal against all four genera of nematodes.

摘要

阿苯达唑是一种广谱驱虫药，对20例患有蛔虫病（10例）、钩虫病（十二指肠钩虫和美洲板口线虫各4例）和鞭虫病（10例）的患者给予400mg单剂量治疗。在治疗前及随后五天采集粪便。对蛔虫和鞭虫卵进行90天的粪便培养，钩虫卵采用原田-森氏技术培养至少八天。阿苯达唑对所有四种线虫均有杀卵作用。