阿苯达唑治疗儿童肠道蠕虫病

Albendazole in the treatment of intestinal helminthiasis in children.

作者信息

Misra P K, Pande N K, Jagota S C

出版信息

Curr Med Res Opin. 1985;9(8):516-9. doi: 10.1185/03007998509109627.

Abstract

A single dose of 2% albendazole suspension (400 mg in 20 ml) was administered to 77 patients (42 males and 35 females), ages ranging between 2 to 12 years, with helminthic infections. Ascariasis was the most prevalent infection. Patients were followed-up for 3 weeks. The results showed that albendazole was highly effective against Ascaris lumbricoides, Ancylostoma duodenale and Enterobius vermicularis. Significant improvement was also observed in patients having infections due to Trichuris trichiura. Albendazole was well tolerated and did not produce any significant side-effects. Single dose albendazole appears to be appropriate for mass chemotherapy to control intestinal nematode infections in highly infected communities.

摘要

对77例年龄在2至12岁、患有蠕虫感染的患者（42名男性和35名女性）给予单剂量2%阿苯达唑混悬液（20毫升含400毫克）。蛔虫病是最常见的感染。对患者进行了3周的随访。结果表明，阿苯达唑对蛔虫、十二指肠钩虫和蛲虫高度有效。对感染鞭虫的患者也观察到显著改善。阿苯达唑耐受性良好，未产生任何明显副作用。单剂量阿苯达唑似乎适合在高感染社区进行群体化疗以控制肠道线虫感染。