Windisch M, Piswanger A
Arzneimittelforschung. 1985;35(1):87-9.
Three peptide preparations, derived from different proteins, and one protein free extract, produced by dialysis of calf blood, were tested. Typical effects of the individual preparations on oxidative metabolism could be shown. A comparable high stimulation of oxygen consumption of brain homogenates by 117 to 165% was measured after application of the peptide derivatives. One of them, the peptide enriched derivative, caused a high and not organ specific stimulation, increasing the oxygen consumption of brain, liver and heart muscle by 165, 203 and 202%, respectively, thus exceeding the effects of the other tested preparations. Extracts of calf blood, which showed maximal stimulation in liver homogenate (98%), led to rather small effects in brain homogenate (51%) compared with those induced by the peptide derivatives.
对三种源自不同蛋白质的肽制剂以及一种通过透析小牛血液产生的无蛋白质提取物进行了测试。可以显示出各个制剂对氧化代谢的典型作用。在应用肽衍生物后，测得脑匀浆的耗氧量有相当高的刺激，增加了117%至165%。其中一种富含肽的衍生物引起了强烈且非器官特异性的刺激，使脑、肝和心肌的耗氧量分别增加了165%、203%和202%，从而超过了其他测试制剂的效果。小牛血液提取物在肝匀浆中显示出最大刺激（98%），但与肽衍生物相比，在脑匀浆中的作用相当小（51%）。
