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[接受来自低动力供体脾细胞移植的完整及部分肝切除小鼠免疫指标的变化]

[Changes in the immunity indices of intact and partially hepatectomized mice undergoing the transplantation of splenic cells from hypokinetic donors].

作者信息

Li S E, Ivanets T A, Turchenko G V

出版信息

Biull Eksp Biol Med. 1985 Apr;99(4):464-5.

PMID:4039205
Abstract

Male (CBA X C57B1/6)F1 mice subjected to a 17-hour movement restrain showed a decrease in splenic and thymic weights and in the number of immunocompetent cells in the blood. Suspension of splenocytes from hypokinetic mice was transplanted to intact and to partly hepatectomized syngeneic animals. One day after transplantation there was a reduction in the weight of the spleen and thymus in intact but not in partly hepatectomized recipients. Seven days after transplantation the number of E-RFC and EAC-RFC dropped in both intact and hepatectomized mice.

摘要

对雄性(CBA×C57B1/6)F1小鼠进行17小时的运动限制后,其脾脏和胸腺重量以及血液中免疫活性细胞数量均有所下降。将运动减少小鼠的脾细胞悬液移植到同基因的完整动物和部分肝切除的动物体内。移植后一天,完整受体的脾脏和胸腺重量减轻,而部分肝切除的受体则没有。移植后七天,完整小鼠和肝切除小鼠的E玫瑰花结形成细胞(E-RFC)和EAC玫瑰花结形成细胞(EAC-RFC)数量均下降。

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