Wei Zhihao, Yu Tengfei, Jin Xufeng, Ma Guanyi, Meng Xianfeng
Department of Trauma Orthopedics, Shengli Oilfield Central Hospital, Dongying City, Shandong Province, China.
Department of Hand and Upper Limb Surgery, Jinan Third People's Hospital, Jinan City, Shandong Province, China.
PLoS One. 2025 May 20;20(5):e0322928. doi: 10.1371/journal.pone.0322928. eCollection 2025.
Sarcopenic obesity is characterized by a combination of obesity and sarcopenia. Body round index (BRI) is a novel anthropometric index that can more accurately assess body and visceral fat levels than body mass index or waist circumference. This study used data from the National Health and Nutrition Examination Survey (NHANES) to explore the relationship between BRI and handgrip strength (HGS) and muscle quality index (MQI) in American adults aged 20 and over.
This study used cross-sectional data from the 2011-2014 National Health and Nutrition Examination Survey (NHANES) with complete data on BRI, HGS, and MQI. We used multivariate linear regression models and smooth curve fitting methods to explore the relationship between BRI and HGS and MQI. In addition, subgroup analyses and interaction tests were performed to further analyze the potential association between these variables.
A total of 5466 participants were finally included in this study, of whom 2807 were males and 2659 were females. The results showed that BRI was positively correlated with HGS and negatively correlated with MQI. In the fully adjusted model, the negative correlation between BRI and MQI was (β= -0.08, 95% CI = -0.08, -0.07), while the positive correlation with HGS was (β= 0.3 8, 95% CI = 0.29, 0.46), indicating that for every unit increase in BRI, MQI decreases by 0.08 units and HGS increases by 0.38 units (P < 0.0001). In addition, the relationship between BRI and HGS is an L-shaped curve. An inflection point is determined when BRI reaches 3.42. Before this threshold, for every unit increase in BRI, HGS increases significantly (β = 2.19, 95% CI = 1.66, 2.72).
The results showed that BRI was positively correlated with HGS and negatively correlated with MQI, meaning that higher BRI was associated with higher HGS and lower MQI. This highlights the importance of body fat distribution in muscle health and suggests that BRI can be used as an effective anthropometric indicator to predict grip strength and muscle mass.
肌少性肥胖的特征是肥胖与肌少症并存。体圆指数（BRI）是一种新型人体测量指数，与体重指数或腰围相比，它能更准确地评估身体和内脏脂肪水平。本研究利用美国国家健康与营养检查调查（NHANES）的数据，探讨20岁及以上美国成年人中BRI与握力（HGS）和肌肉质量指数（MQI）之间的关系。
本研究使用了2011 - 2014年美国国家健康与营养检查调查（NHANES）的横断面数据，这些数据包含了关于BRI、HGS和MQI的完整信息。我们使用多元线性回归模型和平滑曲线拟合方法来探讨BRI与HGS和MQI之间的关系。此外，还进行了亚组分析和交互作用检验，以进一步分析这些变量之间的潜在关联。
本研究最终纳入了5466名参与者，其中男性2807名，女性2659名。结果显示，BRI与HGS呈正相关，与MQI呈负相关。在完全调整模型中，BRI与MQI的负相关为（β = -0.08，95%可信区间 = -0.08，-0.07），而与HGS的正相关为（β = 0.38，95%可信区间 = 0.29，0.46），这表明BRI每增加一个单位，MQI下降0.08个单位，HGS增加0.38个单位（P < 0.0001）。此外，BRI与HGS之间的关系呈L形曲线。当BRI达到3.42时确定一个拐点。在此阈值之前，BRI每增加一个单位，HGS显著增加（β = 2.19，95%可信区间 = 1.66，2.72）。
结果表明，BRI与HGS呈正相关，与MQI呈负相关，这意味着较高的BRI与较高的HGS和较低的MQI相关。这突出了体脂分布在肌肉健康中的重要性，并表明BRI可作为预测握力和肌肉量的有效人体测量指标。
