Tennekoon K H, Lenton E A
J Reprod Fertil. 1985 Mar;73(2):523-7. doi: 10.1530/jrf.0.0730523.
Prolactin concentrations were measured in hourly integrated blood samples collected over 24 h in normally cyclic women during the follicular (N = 8) and the luteal (N = 7) phases of the menstrual cycle. Prolactin concentrations were increased during the evening in all the subjects when compared with the rest of the day-time wake-period. This rise was unrelated to sleep, and peak concentrations were seen at 20:00 h. During the luteal phase the magnitude of this evening rise of prolactin was significantly greater (P less than 0.02 at 19:00 h and P less than 0.001 at 20:00 h) when compared with the follicular phase, and was only slightly smaller than the magnitude of the sleep-induced prolactin rise. It is therefore suggested that there may be an intrinsic rhythm in prolactin secretion apart from the sleep-induced rise.
在月经周期的卵泡期（N = 8）和黄体期（N = 7），对正常月经周期的女性在24小时内每小时采集的全血样本进行催乳素浓度测定。与白天其余清醒时段相比，所有受试者在夜间催乳素浓度均升高。这种升高与睡眠无关，峰值浓度出现在20:00。与卵泡期相比，黄体期夜间催乳素升高幅度显著更大（19:00时P < 0.02，20:00时P < 0.001），且仅略小于睡眠诱导的催乳素升高幅度。因此，提示除睡眠诱导的升高外，催乳素分泌可能存在内在节律。
