Cao Yingpin, Ye Jiajia, Nie Aiqin, Sun Dan, Yang Ming-Ming
Department of Ophthalmology, Shenzhen People's Hospital (The First Affiliated Hospital, Southern University of Science and Technology; The Second Clinical Medical College, Jinan University), Shenzhen, 518020, Guangdong, China.
Hunan Provincial University Key Laboratory of the Fundamental and Clinical Research on Neurodegenerative Diseases, Changsha Medical University, Changsha, 410219, Hunan, China.
Sci Rep. 2025 May 20;15(1):17473. doi: 10.1038/s41598-025-01309-3.
We investigated the differences in binocular vision function and visual fatigue between school-aged children with myopic anisometropia and those with myopic isometropia. It also examined the correlation between myopic anisometropia and binocular vision parameters. One hundred school-aged (ages 6-13 years) children (43 boys and 57 girls) were divided into two groups: the myopic anisometropia group (interocular spherical equivalent difference ≥ 1.50 and < 4.00 D) and the myopic isometropia group as control group (interocular spherical equivalent difference < 1.00 D). Binocular vision parameters related to accommodation were analyzed, including accommodative amplitude, flexibility, relative accommodation, and convergence flexibility. Differences in visual fatigue scores between groups were also evaluated. Patients with myopic anisometropia show significant binocular visual dysfunction, including reduced accommodation amplitude, accommodative facility, and vergence facility, with a compensatory increase in positive relative accommodation. Although negative relative accommodation was similar between groups, anisometropic patients had more severe visual fatigue (higher ASQ-11 scores). In myopic patients without anisometropia, visual fatigue was mildly negatively correlated with accommodative facility. Clinically, binocular accommodation and vergence function should be carefully assessed in myopic patients, especially those with anisometropia, and visual fatigue interventions should include training of accommodative and vergence facility to enhance visual quality.
我们研究了近视性屈光参差学龄儿童与近视性等屈光不正学龄儿童在双眼视觉功能和视觉疲劳方面的差异。同时还研究了近视性屈光参差与双眼视觉参数之间的相关性。将100名学龄（6 - 13岁）儿童（43名男孩和57名女孩）分为两组：近视性屈光参差组（双眼等效球镜度差值≥1.50且<4.00 D）和作为对照组的近视性等屈光不正组（双眼等效球镜度差值<1.00 D）。分析了与调节相关的双眼视觉参数，包括调节幅度、灵活性、相对调节和集合灵活性。还评估了两组之间视觉疲劳评分的差异。近视性屈光参差患者表现出明显的双眼视觉功能障碍，包括调节幅度降低、调节灵活性和聚散灵活性下降，正相对调节有代偿性增加。尽管两组之间负相对调节相似，但屈光参差患者的视觉疲劳更严重（ASQ - 11评分更高）。在无屈光参差的近视患者中，视觉疲劳与调节灵活性呈轻度负相关。临床上，对于近视患者，尤其是屈光参差患者，应仔细评估双眼调节和聚散功能，视觉疲劳干预应包括调节和聚散灵活性训练以提高视觉质量。
