Department of Optometry and Visual Science, West China Hospital, Sichuan University, No. 37, Guoxuexiang, Wuhou District, Chengdu, 610041, Sichuan, China.
Graefes Arch Clin Exp Ophthalmol. 2021 Jul;259(7):2035-2045. doi: 10.1007/s00417-021-05106-2. Epub 2021 Feb 2.
The study aimed to observe and analyze the dynamic accommodation and binocular vision changes in myopic children after they switched from spectacles to orthokeratology (ortho-k) lenses.
Thirty-six myopic children aged 8-14 years were enrolled in this prospective, self-controlled study from West China Hospital. General information was gathered, and examinations were performed at baseline and at 1, 3, 6, and 12 months after switching to ortho-k lenses. The examination included assessments of distance/near visual acuity, distance/near horizontal and vertical ocular alignment, distance/near horizontal vergence range, accommodative amplitude, monocular/binocular accommodative facility, accommodative response, positive and negative relative accommodation (PRA/NRA), accommodation convergence/accommodation (AC/A), stereopsis, and reading ability.
After the children switched to ortho-k lenses, distance and near ocular alignment showed an exophoric shift (distance: p = 0.001, near: p = 0.002), and the horizontal vergence range decreased by different degrees (convergence: distance blur point (p = 0.002), distance break point (p = 0.005), near blur point (p = 0.011), near break point (p = 0.043); divergence: distance break point (p < 0.001), distance recover point (p < 0.001), near recover point (p = 0.005)). The stereopsis ability (p < 0.001), monocular/binocular accommodative facility (p < 0.001), and PRA (p = 0.010) increased. The accommodative lag (p < 0.001), accommodative amplitude (p < 0.001), and calculated and gradient AC/A (calculated: p = 0.001, gradient: p = 0.025) decreased. The adjusted horizontal and vertical reading times and their ratio decreased (all p < 0.001).
The subjects showed distance and near exophoric shifts after switching to ortho-k lenses; improvements in accommodative function, stereopsis, and ocular motility; and a decrease in the binocular horizontal vergence range. The relationships between these changes and the ortho-k myopic control effects require further investigation.
本研究旨在观察和分析近视儿童从戴眼镜切换为角膜塑形术(ortho-k)镜片后动态调节和双眼视觉的变化。
本前瞻性、自身对照研究纳入了 36 名 8-14 岁的近视儿童,他们均来自华西医院。在切换到 ortho-k 镜片之前和之后的 1、3、6 和 12 个月收集一般信息并进行检查。检查包括远/近视力、远/近水平和垂直眼位、远/近水平聚散范围、调节幅度、单眼/双眼调节灵活度、调节反应、正/负相对调节(PRA/NRA)、调节集合/调节(AC/A)、立体视和阅读能力。
儿童切换到 ortho-k 镜片后,远/近眼位出现外隐斜(远距:p = 0.001,近距:p = 0.002),水平聚散范围不同程度下降(集合:远距模糊点(p = 0.002)、远距破裂点(p = 0.005)、近距模糊点(p = 0.011)、近距破裂点(p = 0.043);散开:远距破裂点(p < 0.001)、远距恢复点(p < 0.001)、近距恢复点(p = 0.005))。立体视能(p < 0.001)、单眼/双眼调节灵活度(p < 0.001)和 PRA(p = 0.010)增加。调节滞后(p < 0.001)、调节幅度(p < 0.001)和计算及梯度 AC/A(计算:p = 0.001,梯度:p = 0.025)降低。调整后的水平和垂直阅读时间及其比值均降低(均 p < 0.001)。
儿童切换到 ortho-k 镜片后表现出远/近外隐斜;调节功能、立体视和眼球运动改善;双眼水平聚散范围减小。这些变化与 ortho-k 近视控制效果之间的关系需要进一步研究。