Park Yeon Jung, Cho Hyun Jin, Kim Kiyoung, Won Chang Won, Kim Miji
College of Medicine, Kyung Hee University, Seoul, Korea.
Department of Health Sciences and Technology, College of Medicine, Kyung Hee University, Seoul, Korea.
BMC Geriatr. 2025 May 20;25(1):359. doi: 10.1186/s12877-025-06014-4.
Visual impairment is associated with cognitive dysfunction in older adults; however, a relationship between stereopsis and cognitive function remains unclear. This study aimed to investigate the association between stereopsis and cognitive function in community-dwelling older adults.
A cross-sectional analysis was conducted with data of 1,228 participants aged 74-88 years from the Korean Frailty and Aging Cohort Study. Cognitive function was assessed by the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K). Stereoscopic vision was measured using the Titmus Fly test and recorded in 3 categories according to the angle of stereopsis. Multiple regression analyses were used to investigate the association between stereopsis and cognitive function.
Total 565 men and 663 women were included. Stereopsis was associated with education, residence, and visual acuity (p <.05). Participants with poor and moderate stereopsis were more likely to have cognitive dysfunction than participants with good stereopsis. Poor stereopsis was negatively associated with cognitive function scores in word list memory, word list recall, Trail Making Test-A errors, Trail Making Test-A response time and frontal assessment battery (p <.05). Compared to good stereopsis group, moderate (odds ratio [OR] = 1.60; 95% confidence interval [CI] = 1.08-2.36) and poor (OR = 1.85; 95% CI = 1.24-2.76) stereopsis groups had a higher risk of cognitive impairment even after controlling for several covariates.
Poor stereopsis was associated with cognitive dysfunction and had increased odds for cognitive impairment. Our findings suggest a cross-sectional association between stereopsis and cognitive dysfunction in community-dwelling older adults.
视力障碍与老年人的认知功能障碍有关；然而，立体视觉与认知功能之间的关系仍不清楚。本研究旨在调查社区居住的老年人中立体视觉与认知功能之间的关联。
对韩国衰弱与衰老队列研究中1228名年龄在74 - 88岁的参与者的数据进行横断面分析。认知功能通过韩国版的阿尔茨海默病注册协会评估包（CERAD-K）进行评估。使用Titmus Fly测试测量立体视觉，并根据立体视觉角度记录为3个类别。采用多元回归分析来研究立体视觉与认知功能之间的关联。
共纳入565名男性和663名女性。立体视觉与教育程度、居住情况和视力相关（p <.05）。与具有良好立体视觉的参与者相比，具有较差和中等立体视觉的参与者更有可能出现认知功能障碍。较差的立体视觉与单词列表记忆、单词列表回忆、连线测验A错误、连线测验A反应时间和额叶评估量表的认知功能评分呈负相关（p <.05）。与良好立体视觉组相比，即使在控制了几个协变量后，中等（优势比[OR] = 1.60；95%置信区间[CI] = 1.08 - 2.36）和较差（OR = 1.85；95% CI = 1.24 - 2.76）立体视觉组的认知障碍风险更高。
较差的立体视觉与认知功能障碍有关，且认知障碍的几率增加。我们的研究结果表明社区居住的老年人中立体视觉与认知功能障碍之间存在横断面关联。
