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氩激光光凝术后糖尿病视网膜的视网膜功能:视网膜电图评估

Retinal function of the diabetic retina after argon laser photocoagulation assessed electroretinographically.

作者信息

Perlman I, Gdal-On M, Miller B, Zonis S

出版信息

Br J Ophthalmol. 1985 Apr;69(4):240-6. doi: 10.1136/bjo.69.4.240.

DOI:10.1136/bjo.69.4.240
PMID:4039601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1040575/
Abstract

Electroretinographic (ERG) responses were measured in diabetic patients before, during, and after panretinal photocoagulation treatment with argon laser. The laser applications reduced considerably the amplitudes of the a and b waves of the ERG. Moreover, the relationship between the amplitude of the b wave and that of the a wave was severely affected, resulting in ERG responses of abnormal pattern. The b waves were smaller than expected from the a waves. These findings indicated that the photocoagulation treatment not only destroyed the retinal areas directly illuminated by the laser beam, but also affected the functional integrity of adjacent areas. These additional effects resulted in subnormal signal transmission from the photoreceptors to the proximal retina.

摘要

对糖尿病患者在氩激光全视网膜光凝治疗前、治疗期间和治疗后进行了视网膜电图(ERG)反应测量。激光照射使ERG的a波和b波振幅大幅降低。此外,b波振幅与a波振幅之间的关系受到严重影响,导致ERG反应模式异常。b波比根据a波预期的要小。这些发现表明,光凝治疗不仅破坏了激光束直接照射的视网膜区域,还影响了相邻区域的功能完整性。这些额外的影响导致从光感受器到视网膜近端的信号传递低于正常水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77c7/1040575/13a9529b5619/brjopthal00136-0006-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77c7/1040575/13a9529b5619/brjopthal00136-0006-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77c7/1040575/13a9529b5619/brjopthal00136-0006-a.jpg

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本文引用的文献

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Br J Ophthalmol. 1983 Aug;67(8):520-5. doi: 10.1136/bjo.67.8.520.
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Relationship between the amplitudes of the b wave and the a wave as a useful index for evaluating the electroretinogram.
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增殖性糖尿病视网膜病变行序贯性全视网膜光凝术后的视网膜电图变化
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Electroretinogram evaluation for the treatment of proliferative diabetic retinopathy by short-pulse pattern scanning laser panretinal photocoagulation.短脉冲模式扫描激光全视网膜光凝治疗增殖性糖尿病视网膜病变的视网膜电图评估
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Photopic full-field electroretinography and optical coherence tomography in type 1 diabetic retinopathy.1型糖尿病视网膜病变的明视全视野视网膜电图和光学相干断层扫描
Graefes Arch Clin Exp Ophthalmol. 2015 Jul;253(7):989-97. doi: 10.1007/s00417-015-3034-y. Epub 2015 May 26.
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Electroretinographic findings associated with panretinal photocoagulation (PRP) versus PRP plus intravitreal ranibizumab treatment for high-risk proliferative diabetic retinopathy.全视网膜光凝(PRP)与PRP联合玻璃体内注射雷珠单抗治疗高危增殖性糖尿病视网膜病变的视网膜电图检查结果
Doc Ophthalmol. 2012 Jun;124(3):225-36. doi: 10.1007/s10633-012-9322-5. Epub 2012 Mar 29.
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