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[急性二氯乙烷中毒时大鼠肝脏和心肌碳酸酐酶活性分布的变化(组织光度学研究)]

[Change in the distribution of rat liver and myocardial carbonic anhydras activity in acute dichloroethane pisoning (histophotometric study)].

作者信息

Sergeev S N, Berezhnoĭ R V

出版信息

Biull Eksp Biol Med. 1977 Jan;83(1):91-3.

PMID:403976
Abstract

A study was made of the histochemical changes in the distribution of the carboanhydrase activity in the myocardium and the liver of rats in acute oral dichlorethane poisoning. Kurate's method modified by Hausler was used. The histophotometric method was applied for the semiquantitative assessment of the changes in the enzyme activity. The majority of the experimental animals displayed a distinct increase in the activity of carboanhydrase in the myocardium and the liver, the correlation of these changes remained the same as in the intact rats.

摘要

对急性经口二氯乙烷中毒大鼠心肌和肝脏中碳酸酐酶活性分布的组织化学变化进行了研究。采用了豪斯勒改良的库拉特方法。应用组织光度法对酶活性变化进行半定量评估。大多数实验动物的心肌和肝脏中碳酸酐酶活性明显增加,这些变化的相关性与正常大鼠相同。

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