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[二氯乙烷急性经口中毒时神经系统的形态学变化]

[Morphologic changes in the nervous system in acute oral poisoning with dichloroethane].

作者信息

Akimov G A, Kolesnichenko I P

出版信息

Arkh Patol. 1978;40(5):49-53.

PMID:686989
Abstract

The nervous system of 14 patients dying of acute oral poisoning with dichloroethane was examined morphologically. Considerable vascular disorders (perivascular edema, congestive plethora, vascular dystony, small focal hemorrhages) and diffuse changes in the cerebral cells were found. The main forms of parenchymatous changes in the brain and spinal cord were acute swelling, shrinking, severe disease and ischemic changes in the nerve cells which occurred within 3--6 hours after taking dichlorethane. Pathomorphology of fibers of the spinal cord and peripheral nerves was presented by moderately marked myelin degeneration.

摘要

对14例死于二氯乙烷急性口服中毒患者的神经系统进行了形态学检查。发现有相当严重的血管病变(血管周围水肿、充血性多血、血管张力障碍、小灶性出血)以及大脑细胞的弥漫性变化。脑和脊髓实质变化的主要形式为急性肿胀、萎缩、严重病变以及在摄入二氯乙烷后3至6小时内神经细胞出现的缺血性变化。脊髓和周围神经纤维的病理形态学表现为中度明显的髓鞘变性。

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