[1,2-二氯乙烷处理的白鼠血清β-N-乙酰氨基葡萄糖苷酶活性研究]
[Study of serum beta-N-acetylglucosaminidase activity in white rats treated with 1,2-dichloroethane].
作者信息
Apostolov I, Mikhaĭlova A
出版信息
Probl Khig. 1975;1:161-4.
PMID:1235995
Abstract
In the course of a three-month long, chronic experiment using white male rats, the organic solvent 1,2-dichlorethane was administered per os at the following doses: 1/5000, 1/1000 and 1/200 LD50. The activity of the lysosome enzyme beta-N-acetylglucosaminidase is studied. A statistically significant increase (p less than 0.02) is established in the two higher doses.
摘要
在一项为期三个月的慢性实验中，使用雄性白鼠，经口给予有机溶剂1,2 - 二氯乙烷，剂量如下：1/5000、1/1000和1/20半数致死量（LD50）。研究了溶酶体酶β - N - 乙酰氨基葡萄糖苷酶的活性。在两个较高剂量组中发现有统计学意义的增加（p小于0.02）。
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