Bhogal Pervinder, Dhillon Permesh Singh, Flood Richard, Lewis Martin, Podlasek Anna, Wong Ken, Lansley Joseph, Makalanda Levansri, Minks David, Spooner Oliver, Mortimer Alex
Department of Interventional Neuroradiology, The Royal London Hospital, Barts NHS Trust, London, UK.
Radiological Sciences, Mental Health & Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.
Interv Neuroradiol. 2025 May 21:15910199251336935. doi: 10.1177/15910199251336935.
BackgroundWe report our initial experience on the use of the Walrus, a new generation balloon guide catheter (BGC) capable of accommodating large bore aspiration catheters for patients undergoing endovascular stroke thrombectomy for large vessel occlusion with a particular focus on procedural aspects related to the vascular anatomy, recanalisation efficacy and complications.MethodsThis is a retrospective, site-adjudicated, two-centre study on consecutive patients with anterior circulation large vessel occlusion treated with the Walrus BGC. Baseline characteristics and procedural and clinical outcomes were analysed.ResultsBetween July 2023 and January 2024, we recruited 300 participants (mean age 69.5 ± 15 years; 132 (44%) females). The mean admission NIHSS was 15.8 ± 6.5, and the mean ASPECTS was 7.6 ± 1.9. Combined stent-retriever and aspiration first-line thrombectomy technique was performed in 235 patients (79%). The Walrus BGC was successfully navigated to the ICA in 99.7% of patients. Near complete-complete recanalisation (eTICI2c-3) was achieved in 75.4% of patients, and the eTICI2b-3 rate was 92.2%. First-pass effect (eTICI2c-3) was achieved in 49% of patients, and the modified first-pass effect (eTICI2b-3) was 65.9%. No significant difference in the arterial puncture-to-guide catheter placement time across the three different arch types ( = .52) or between the favourable and unfavourable ASMETS score ( = .085) was observed. Any intracranial haemorrhage (ICH) occurred in 14.9% of patients, and symptomatic ICH in 3.9%.ConclusionUse of the Walrus large bore BGC during endovascular stroke thrombectomy appears effective in reaching the target vessel without a significant time penalty across various anatomical configurations and tortuosity, whilst maintaining a satisfactory safety profile.
背景
我们报告了使用海象(Walrus)的初步经验,这是一种新一代球囊导引导管(BGC),能够容纳大口径抽吸导管,用于接受血管内卒中血栓切除术治疗大血管闭塞的患者,特别关注与血管解剖、再通疗效和并发症相关的操作方面。
方法
这是一项回顾性、多中心判定的两中心研究,研究对象为连续使用海象BGC治疗的前循环大血管闭塞患者。分析了基线特征、操作和临床结果。
结果
在2023年7月至2024年1月期间,我们招募了300名参与者(平均年龄69.5±15岁;132名(44%)女性)。入院时美国国立卫生研究院卒中量表(NIHSS)评分平均为15.8±6.5,脑缺血半暗带早期CT评分(ASPECTS)平均为7.6±1.9。235例患者(79%)采用了联合支架取栓器和抽吸的一线血栓切除术技术。99.7%的患者中海象BGC成功送达颈内动脉(ICA)。75.4%的患者实现了近乎完全至完全再通(脑梗死溶栓分级量表(eTICI)2c-3级),eTICI 2b-3级率为92.2%。49%的患者实现了首次通过效应(eTICI 2c-3级),改良首次通过效应(eTICI 2b-3级)为65.9%。在三种不同弓型之间(P = 0.52)或有利和不利的动脉粥样硬化性狭窄和迂曲评分(ASMETS)之间(P = 0.085),动脉穿刺至导引导管置入时间没有显著差异。14.9%的患者发生了任何颅内出血(ICH),3.9%的患者发生了有症状ICH。
结论
在血管内卒中血栓切除术中使用海象大口径BGC似乎能有效到达目标血管,在各种解剖结构和迂曲情况下不会造成显著的时间延误,同时保持令人满意的安全性。