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Temporary blood flow arrest during endovascular thrombectomy for acute ischaemic stroke.急性缺血性卒中血管内血栓切除术期间的临时血流阻断
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3
Balloon guide catheters for endovascular thrombectomy in patients with acute ischaemic stroke due to large-vessel occlusion in China (PROTECT-MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial.中国急性大血管闭塞性缺血性卒中血管内取栓中使用球囊引导导管(PROTECT-MT):一项多中心、开放标签、盲终点、随机对照试验。
Lancet. 2024 Nov 30;404(10468):2165-2174. doi: 10.1016/S0140-6736(24)02315-8. Epub 2024 Nov 20.
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Comparison of Balloon Guide Catheters and Standard Guide Catheters for Acute Ischemic Stroke: An Updated Systematic Review and Meta-analysis.球囊导引导管与标准导引导管在急性缺血性脑卒中治疗中的比较:一项更新的系统评价和荟萃分析。
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5
First experience with Walrus balloon guide catheter in a whole-body flow model.在全身体模型中使用 Walrus 球囊导引导管的首次体验。
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6
Endovascular thrombectomy first-pass reperfusion and ancillary device placement.血管内血栓切除术初次通过再灌注和辅助装置放置。
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Addition of intracranial aspiration to balloon guide catheter does not improve outcomes in large vessel occlusion anterior circulation stent retriever based thrombectomy for acute stroke.颅内抽吸联合球囊引导导管不能改善急性缺血性脑卒中血管内支架取栓治疗中前循环大血管闭塞患者的预后。
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海象球囊引导导管的初步经验——来自两个高容量血栓切除术中心的结果。

The initial experience with the Walrus balloon guide catheter - Results from two high-volume thrombectomy centres.

作者信息

Bhogal Pervinder, Dhillon Permesh Singh, Flood Richard, Lewis Martin, Podlasek Anna, Wong Ken, Lansley Joseph, Makalanda Levansri, Minks David, Spooner Oliver, Mortimer Alex

机构信息

Department of Interventional Neuroradiology, The Royal London Hospital, Barts NHS Trust, London, UK.

Radiological Sciences, Mental Health & Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK.

出版信息

Interv Neuroradiol. 2025 May 21:15910199251336935. doi: 10.1177/15910199251336935.

DOI:10.1177/15910199251336935
PMID:40398475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12095199/
Abstract

BackgroundWe report our initial experience on the use of the Walrus, a new generation balloon guide catheter (BGC) capable of accommodating large bore aspiration catheters for patients undergoing endovascular stroke thrombectomy for large vessel occlusion with a particular focus on procedural aspects related to the vascular anatomy, recanalisation efficacy and complications.MethodsThis is a retrospective, site-adjudicated, two-centre study on consecutive patients with anterior circulation large vessel occlusion treated with the Walrus BGC. Baseline characteristics and procedural and clinical outcomes were analysed.ResultsBetween July 2023 and January 2024, we recruited 300 participants (mean age 69.5 ± 15 years; 132 (44%) females). The mean admission NIHSS was 15.8 ± 6.5, and the mean ASPECTS was 7.6 ± 1.9. Combined stent-retriever and aspiration first-line thrombectomy technique was performed in 235 patients (79%). The Walrus BGC was successfully navigated to the ICA in 99.7% of patients. Near complete-complete recanalisation (eTICI2c-3) was achieved in 75.4% of patients, and the eTICI2b-3 rate was 92.2%. First-pass effect (eTICI2c-3) was achieved in 49% of patients, and the modified first-pass effect (eTICI2b-3) was 65.9%. No significant difference in the arterial puncture-to-guide catheter placement time across the three different arch types ( = .52) or between the favourable and unfavourable ASMETS score ( = .085) was observed. Any intracranial haemorrhage (ICH) occurred in 14.9% of patients, and symptomatic ICH in 3.9%.ConclusionUse of the Walrus large bore BGC during endovascular stroke thrombectomy appears effective in reaching the target vessel without a significant time penalty across various anatomical configurations and tortuosity, whilst maintaining a satisfactory safety profile.

摘要

背景

我们报告了使用海象(Walrus)的初步经验,这是一种新一代球囊导引导管(BGC),能够容纳大口径抽吸导管,用于接受血管内卒中血栓切除术治疗大血管闭塞的患者,特别关注与血管解剖、再通疗效和并发症相关的操作方面。

方法

这是一项回顾性、多中心判定的两中心研究,研究对象为连续使用海象BGC治疗的前循环大血管闭塞患者。分析了基线特征、操作和临床结果。

结果

在2023年7月至2024年1月期间,我们招募了300名参与者(平均年龄69.5±15岁;132名(44%)女性)。入院时美国国立卫生研究院卒中量表(NIHSS)评分平均为15.8±6.5,脑缺血半暗带早期CT评分(ASPECTS)平均为7.6±1.9。235例患者(79%)采用了联合支架取栓器和抽吸的一线血栓切除术技术。99.7%的患者中海象BGC成功送达颈内动脉(ICA)。75.4%的患者实现了近乎完全至完全再通(脑梗死溶栓分级量表(eTICI)2c-3级),eTICI 2b-3级率为92.2%。49%的患者实现了首次通过效应(eTICI 2c-3级),改良首次通过效应(eTICI 2b-3级)为65.9%。在三种不同弓型之间(P = 0.52)或有利和不利的动脉粥样硬化性狭窄和迂曲评分(ASMETS)之间(P = 0.085),动脉穿刺至导引导管置入时间没有显著差异。14.9%的患者发生了任何颅内出血(ICH),3.9%的患者发生了有症状ICH。

结论

在血管内卒中血栓切除术中使用海象大口径BGC似乎能有效到达目标血管,在各种解剖结构和迂曲情况下不会造成显著的时间延误,同时保持令人满意的安全性。