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两项基于社区实践的简短干预措施对自我伤害和自杀意念影响的实用性随机对照试验。

Pragmatic randomised controlled trial of two brief community practice-based interventions for self-harm and suicidal ideation.

作者信息

Lockwood Joanna, Goodwin Tom, Freeman Katie, Harroe Caroline

机构信息

Mental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, UK

NIHR MindTech HealthTech Research Centre, University of Nottingham, Nottingham, UK.

出版信息

BMJ Ment Health. 2025 May 21;28(1):e301601. doi: 10.1136/bmjment-2025-301601.

Abstract

BACKGROUND

Improving preventative interventions for self-harm and suicide-related behaviour is a mental health policy priority. Existing evidence-based interventions can be lengthy, resource-heavy, difficult to access, and are not always acceptable or effective. Extending support through brief and remotely delivered interventions outside of brings potential to expand access to timely and effective support.

OBJECTIVE

The primary objective is to assess the effectiveness of two brief (6 week) interventions (Integrative Therapy and Stabilisation) in reducing self-harm frequency.

METHODS

We evaluated data from a practice-based randomised controlled trial of hybrid Integrative Therapy and Stabilisation utilising a no-treatment control group to determine the effectiveness of each intervention targeting frequency of self-harm (primary outcome), suicidal ideation and depressive symptoms (secondary outcomes). Participants, 82 help-seeking adults with current self-harm behaviour aged 18-59 years (mean age30.57, SD=12.5), received either Stabilisation (n=25) or Integrative Psychotherapy (n=25) or were assigned to a control waitlist (n=32). Six 1-hour sessions were delivered via video call in a 1:1 format. Outcome measures were completed at baseline and immediately postintervention.

FINDINGS

In comparison to waitlist controls, those receiving Stabilisation had greater reductions preintervention to postintervention in self-harm frequency, suicidal ideation and depressive symptoms. Those receiving Integrative Psychotherapy had greater reductions in self-harm frequency and suicidal ideation, but not depression symptoms, compared with waitlist.

CONCLUSIONS

Interventions delivered in a service setting show promise in improving outcomes for self-harm and suicidal ideation, and to a lesser extent depression symptoms, over a 6-week period. Further evaluation and replication, including in longitudinal studies and fully randomised controlled trials, would be needed to build on these preliminary findings and extend beyond the current setting.

CLINICAL IMPLICATIONS

Short, remotely delivered interventions outside of traditional clinical settings may offer an effective and timely treatment option.

摘要

背景

改善针对自我伤害及自杀相关行为的预防干预措施是心理健康政策的重点。现有的循证干预措施可能耗时较长、资源需求大、难以获得,且并非总是可接受或有效的。通过简短且远程提供的干预措施来扩大支持范围,有可能增加获得及时有效支持的机会。

目的

主要目的是评估两种简短(6周)干预措施(综合疗法和稳定疗法)在降低自我伤害频率方面的有效性。

方法

我们评估了一项基于实践的随机对照试验的数据,该试验采用混合的综合疗法和稳定疗法,并设置了一个无治疗对照组,以确定每种干预措施针对自我伤害频率(主要结局)、自杀意念和抑郁症状(次要结局)的有效性。参与者为82名年龄在18至59岁(平均年龄30.57岁,标准差=12.5)、有当前自我伤害行为且寻求帮助的成年人,他们分别接受稳定疗法(n=25)或综合心理治疗(n=25),或被分配到对照等待名单(n=32)。通过视频通话以一对一的形式进行六次1小时的疗程。结局指标在基线和干预后立即完成。

结果

与等待名单对照组相比,接受稳定疗法的人在干预前到干预后自我伤害频率、自杀意念和抑郁症状的降低幅度更大。与等待名单相比,接受综合心理治疗的人在自我伤害频率和自杀意念方面的降低幅度更大,但在抑郁症状方面没有。

结论

在服务环境中提供的干预措施在改善自我伤害和自杀意念结局方面显示出前景,在较小程度上也改善了抑郁症状,为期6周。需要进一步的评估和重复研究,包括纵向研究和完全随机对照试验,以基于这些初步发现并超越当前环境进行拓展。

临床意义

在传统临床环境之外进行的简短远程干预措施可能提供一种有效且及时的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd5a/12097079/79366266d184/bmjment-28-1-g001.jpg

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