Addis Zemenu, Berhie Alemeshet Yirga, Abate Teshager Woldegiyorgis, Belay Bekalu Mekonen, Wale Habtam, Tega Ayenew, Alene Tamiru
Department of Clinical Nursing, Hosanna College of Health Science, Hosanna, Ethiopia
Department of Adult Health Nursing, College of Medicine and Health Sciences, School of Health, Bahir Dar University, Bahirdar, Ethiopia.
BMJ Open. 2025 May 21;15(5):e086054. doi: 10.1136/bmjopen-2024-086054.
The burden of comorbid cardiovascular disease (CVD) and its preventable factors in type 2 diabetes is not well acknowledged in Ethiopia. Therefore, this study aimed to identify the magnitude of comorbidity of CVD and predictors among individuals with type 2 diabetes.
A multicentre hospital-based cross-sectional study.
Bahir Dar city Administration Public Hospitals, Ethiopia.
Data on comorbid CVDs among individuals with type 2 diabetes were collected through patient chart reviews. To identify predictors of CVDs in type 2 diabetes, information on lifestyle and psychosocial characteristics, medication and dietary adherence, and disease management status was collected using standardised questionnaires. Statistical analyses were performed using SPSS V.26. The level of statistical significance was set at p<0.05, with ORs and 95% CIs.
The participants' mean age (±SD) was 51.5±10.9 years. The overall prevalence of comorbid CVDs among type 2 diabetes was 27.9% (95% CI 23.6% to 32.3%). Factors that statistically predicted the occurrence of comorbid CVDs in type 2 diabetes were: age >60 years (adjusted ORs (AORs)=2.6, 95% CI 1.1 to 6.6), non-adherence to diabetes-friendly diet (AOR=4.0, 95% CI 1.9 to 8.2), low medication adherence (AOR=2.8, 95% CI 1.5 to 5.3), being overweight (AOR=5.3, 95% CI 2.9 to 9.8), and diabetes duration >10 years (AOR=3.7, 95% CI 1.7 to 8.1).
Comorbid cardiovascular disease is a significant issue among type 2 diabetic patients. Its prevalence is higher in patients over 60 years of age, with modifiable factors identified as key contributors. Appropriate interventions are recommended, including educating type 2 diabetic patients on dietary regimens, medication adherence, weight management, and the benefits of timely healthcare for effective disease management.
在埃塞俄比亚,2型糖尿病患者中合并心血管疾病(CVD)及其可预防因素的负担尚未得到充分认识。因此,本研究旨在确定2型糖尿病患者中CVD合并症的严重程度及其预测因素。
一项基于多中心医院的横断面研究。
埃塞俄比亚巴赫达尔市行政区公立医院。
通过查阅患者病历收集2型糖尿病患者合并CVD的数据。为了确定2型糖尿病中CVD的预测因素,使用标准化问卷收集了生活方式和心理社会特征、药物和饮食依从性以及疾病管理状况的信息。使用SPSS V.26进行统计分析。统计学显著性水平设定为p<0.05,并计算比值比(OR)和95%置信区间(CI)。
参与者的平均年龄(±标准差)为51.5±10.9岁。2型糖尿病患者中合并CVD的总体患病率为27.9%(95%CI 23.6%至32.3%)。在2型糖尿病中,统计学上预测合并CVD发生的因素包括:年龄>60岁(调整后的OR(AOR)=2.6,95%CI 1.1至6.6)、不坚持糖尿病友好型饮食(AOR=4.0,95%CI 1.9至8.2)、药物依从性低(AOR=2.8,95%CI 1.5至5.3)、超重(AOR=5.3,95%CI 2.9至9.8)以及糖尿病病程>10年(AOR=3.7,95%CI 1.7至8.1)。
合并心血管疾病是2型糖尿病患者中的一个重要问题。在60岁以上的患者中患病率更高,已确定可改变的因素是主要促成因素。建议采取适当的干预措施,包括对2型糖尿病患者进行饮食方案、药物依从性、体重管理以及及时就医对有效疾病管理的益处等方面的教育。