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2023年埃塞俄比亚巴赫达尔费莱格希沃特转诊医院成年2型糖尿病患者的血脂异常及相关因素

Dyslipidemia and associated factors among adult type two diabetes mellitus patients in Felege Hiywot Refral, Hospital, Bahir Dar, Ethiopia, 2023.

作者信息

Addis Zemenu, Nega Ayenew Tega, Tebeje Robel Demelash, Asmare Engdaw, Tegegnie Alemu Bezabih, Tamir Workineh, Alene Tamiru

机构信息

Department of Clinical Nursing, Hosanna Health Science College, Hosanna, Ethiopia.

Department of Midwifery, Hosanna Health Science College, Hosanna, Ethiopia.

出版信息

Front Cardiovasc Med. 2024 Dec 20;11:1493447. doi: 10.3389/fcvm.2024.1493447. eCollection 2024.

Abstract

BACKGROUND

Dyslipidemia is a common condition in type two diabetic patients, and it is thought to have a significant role in moderating the cardiovascular risk associated with diabetes. Data on serum lipid profiles in type 2 diabetes patients from Bahir Dar, Ethiopia is limited. This study aimed to evaluate the prevalence of dyslipidemia among adult type 2 diabetes patients and to explore potential contributing factors.

METHOD AND MATERIALS

A facility-based cross-sectional study was conducted with 354 type 2 diabetes mellitus patients from April 3 to June 4, 2023. Data were collected through the use of structured questionnaires and checklists. The data were entered into EpiData version 4.6 and analyzed using SPSS version 26. Logistic regression was employed to identify variables significantly associated with the outcomes, with a -value ≤ 0.05 and a 95% confidence interval.

RESULTS

A total of 369 individuals with diabetes were approached in this study, resulting in a response rate of 96%. The overall prevalence of dyslipidemia was 61.3% (95% CI: 56.2-66.7). Of those with dyslipidemia, 11% had a single serum lipid abnormality, while 50.3% had a combined serum lipid abnormality. Significant factors associated with dyslipidemia included being over 60 years old (AOR: 2.4, 95% CI: 1.2-5.0), poor fasting blood glucose control (AOR: 2.5, 95% CI: 1.2-5.1), being overweight (AOR: 5.8, 95% CI: 3.2-11), physical inactivity (AOR: 3.4, 95% CI: 1.7-7.0), and being a past alcohol drinker (AOR: 3.1, 95% CI: 1.3-7.4).

CONCLUSION

In the study area, a high prevalence of dyslipidemia was found among diabetic patients. Independent factors associated with dyslipidemia included older age, poor fasting blood glucose control, physical inactivity, a history of alcohol consumption, and being overweight. To address this issue, it is essential to implement preventive measures such as early detection, patient education, dietary monitoring, regular clinical visits, physical exercise, and weight management. These strategies represent the most effective approach to combating dyslipidemia.

摘要

背景

血脂异常在2型糖尿病患者中很常见,并且被认为在调节与糖尿病相关的心血管风险方面起着重要作用。来自埃塞俄比亚巴赫达尔的2型糖尿病患者的血脂谱数据有限。本研究旨在评估成年2型糖尿病患者中血脂异常的患病率,并探索潜在的影响因素。

方法与材料

2023年4月3日至6月4日,对354例2型糖尿病患者进行了一项基于机构的横断面研究。通过使用结构化问卷和检查表收集数据。数据录入EpiData 4.6版本,并使用SPSS 26版本进行分析。采用逻辑回归来确定与结果显著相关的变量,P值≤0.05且置信区间为95%。

结果

本研究共接触了369例糖尿病患者,应答率为96%。血脂异常的总体患病率为61.3%(95%置信区间:56.2 - 66.7)。在血脂异常患者中,11%有单一血脂异常,而50.3%有复合血脂异常。与血脂异常相关的显著因素包括年龄超过60岁(比值比:2.4,95%置信区间:1.2 - 5.0)、空腹血糖控制不佳(比值比:2.5,95%置信区间:1.2 - 5.1)、超重(比值比:5.8,95%置信区间:3.2 - 11)、缺乏体育活动(比值比:3.4,95%置信区间:1.7 - 7.0)以及既往饮酒(比值比:3.1,95%置信区间:1.3 - 7.4)。

结论

在研究区域,糖尿病患者中血脂异常的患病率较高。与血脂异常相关的独立因素包括年龄较大、空腹血糖控制不佳、缺乏体育活动、饮酒史以及超重。为解决这一问题,实施诸如早期检测、患者教育、饮食监测、定期临床就诊、体育锻炼和体重管理等预防措施至关重要。这些策略是对抗血脂异常最有效的方法。

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