[先天性心脏缺陷作为死产和婴儿死亡的一个原因]

[Congenital heart defects as a cause of still birth and infant mortality].

作者信息

Busch R, Voigt M, Rothe J

出版信息

Gegenbaurs Morphol Jahrb. 1985;131(2):253-9.

Abstract

Among 4,686 still-births and children died from 0 to 1 a in the German Democratic Republic in 1979 there were 307 (6.6%) isolated congenital heart diseases. We only analyzed 294 died infants. The first 5 diagnoses were: Hypoplastic left heart (all infants died within the first 28 d) 9.9%, Ventricular septal defect 9.9%, Transposition of great vessels 8.8%, Coarctation aorta 7.1%, Common truncus arteriosus 5.8%. The most important results are an interesting frequency with advancing years of mothers (3.4% in 10,000 mothers of live-births aged 16 a and less to 20.6% at the age of 40 a and over (see Fig. 1), 13% premature children (under 37 weeks of gestation), 23% children under 2,500 g birth weight, 55% boys and 45% girls. 80% of the above 294 infants died within the first 3 months.

摘要

1979年在德意志民主共和国，4686例死产儿及出生后0至1岁死亡的儿童中，有307例（6.6%）患有单纯先天性心脏病。我们仅分析了294例死亡婴儿。前5种诊断结果为：左心发育不全（所有婴儿均在出生后28天内死亡）9.9%，室间隔缺损9.9%，大动脉转位8.8%，主动脉缩窄7.1%，共同动脉干5.8%。最重要的结果是，随着母亲年龄增长发病率呈现有趣的变化（16岁及以下活产母亲每10000人中有3.4%，40岁及以上母亲中为20.6%（见图1）），13%为早产儿（妊娠不足37周），23%出生体重低于2500克，55%为男孩，45%为女孩。上述294例婴儿中有80%在出生后前3个月内死亡。