Legierse Ivo P, van Middendorp Henriët, Borgonjen Maike, Bronkhorst Ewald M, Pisters Martijn F, Vissers Kris C P, Steegers Monique A H
Department of Anaesthesiology, Pain and Palliative Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands.
Health, Medical and Neuropsychology Unit, Faculty of Social and Behavioural Sciences, Institute of Psychology, Leiden University, Leiden, the Netherlands.
Pain Pract. 2025 Jun;25(5):e70047. doi: 10.1111/papr.70047.
This study examined the feasibility of a research protocol for assessing psychological flexibility in patients with chronic pain to gain insight into the uniqueness of different phenotypes of psychological flexibility and to tentatively test whether psychological flexibility is associated with effective adaptation to chronic pain.
In a cross-sectional study, in twenty patients with chronic pain, different phenotypes of psychological flexibility and a variety of positive and negative health indicators were assessed. Correlations were explored to determine the unicity of the different phenotypes of psychological flexibility and to test their associations with chronic pain.
All phenotypes of psychological flexibility could be assessed reliably in this patient group. Preliminary findings suggest that all phenotypes assess unique flexibility aspects (79% of the intercorrelations were less than moderate; > -0.30, < 0.30). Higher levels of different psychological flexibility phenotypes were generally associated with higher positive health indicators and lower negative health indicators (70% of the moderate correlations; ≤ -0.30 or ≥ 0.30 were in the expected direction).
Results confirm that the protocol is feasible for large-scale research in patients with chronic pain and that it is useful to further investigate the different phenotypes of psychological flexibility in relation to optimal adaptation to chronic pain in a longitudinal study.
Psychological flexibility is a potentially important future target in the treatment (e.g., biofeedback, cognitive behavioral therapy, mindfulness) of patients with chronic pain.
本研究探讨了一项研究方案的可行性,该方案旨在评估慢性疼痛患者的心理灵活性,以深入了解心理灵活性不同表型的独特性,并初步测试心理灵活性是否与对慢性疼痛的有效适应相关。
在一项横断面研究中,对20名慢性疼痛患者评估了心理灵活性的不同表型以及各种正面和负面健康指标。通过探索相关性来确定心理灵活性不同表型的独特性,并测试它们与慢性疼痛的关联。
在该患者群体中,可以可靠地评估心理灵活性的所有表型。初步研究结果表明,所有表型评估的都是独特的灵活性方面(79%的相互关联程度为低度;>-0.30,<0.30)。不同心理灵活性表型的较高水平通常与较高的正面健康指标和较低的负面健康指标相关(70%的中度相关性;≤-0.30或≥0.30符合预期方向)。
结果证实该方案对于慢性疼痛患者的大规模研究是可行的,并且在纵向研究中进一步调查心理灵活性的不同表型与对慢性疼痛的最佳适应之间的关系是有用的。
心理灵活性是慢性疼痛患者治疗(如生物反馈、认知行为疗法、正念)中一个潜在的重要未来靶点。