Khalil Abdalla, Oldham Naomi, Beepaul Saju, Chang Elvin
Acute Medicine, Northwick Park Hospital London, London, GBR.
Dermatology, Northwick Park Hospital London, London, GBR.
Cureus. 2025 Apr 21;17(4):e82735. doi: 10.7759/cureus.82735. eCollection 2025 Apr.
Immunoglobulin A vasculitis (IgAV) is a small vessel vasculitis that mainly affects the skin, gastrointestinal tract, and kidneys. We present a case of a middle-aged male patient who presented to the emergency department with lower chest pain, colicky abdominal pain, and painful petechial rash. His inflammatory markers and IgA were raised with mild proteinuria. Abdominal CT and endoscopy revealed gastrointestinal involvement, and immunofluorescence skin biopsy confirmed IgA deposition in the dermal vessels. He responded clinically to oral steroids, and his inflammatory markers trended down. After six days, he was discharged.
免疫球蛋白A血管炎(IgAV)是一种主要累及皮肤、胃肠道和肾脏的小血管血管炎。我们报告一例中年男性患者,他因下胸痛、绞痛性腹痛和疼痛性瘀点皮疹就诊于急诊科。他的炎症标志物和IgA升高,伴有轻度蛋白尿。腹部CT和内镜检查显示胃肠道受累,免疫荧光皮肤活检证实真皮血管中有IgA沉积。他对口服类固醇有临床反应,炎症标志物呈下降趋势。六天后,他出院了。