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用类固醇治疗老年患者的免疫球蛋白 A 血管炎:一项临床研究。

Treating Immunoglobulin A Vasculitis in an Elderly Patient Using Steroids: A Clinical Study.

机构信息

Department of Gastroenterological Surgery, Shiroyama Hospital, Gunma, Japan

Department of Gastroenterological & General Surgery School of Medicine, Showa University, Tokyo, Japan.

出版信息

In Vivo. 2019 Jul-Aug;33(4):1325-1328. doi: 10.21873/invivo.11606.

DOI:10.21873/invivo.11606
PMID:31280225
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6689334/
Abstract

Herein, we report a case of immunoglobulin A vasculitis (IgAV) onset in an elderly patient. A 61-year-old male presented to our hospital with palpable purpura on his right leg and abdomen and diffuse abdominal pain. Computed tomography revealed thickened intestinal wall and ascites. In addition, his serum IgA and urinary protein levels were elevated. The histopathological finding of palpable purpura indicated vasculitis, and he was diagnosed with IgAV. Accordingly, steroid therapy was initiated. Gradually, purpura and abdominal pain disappeared, and he was discharged on day 26 after admission. Although IgAV is common in children, only few cases have been reported in elderly. Thus, when examining patients, including elderly, with palpable purpura and abdominal pain, the possibility of IgAV should be considered.

摘要

在此,我们报告一例老年患者免疫球蛋白 A 血管炎(IgAV)发病。一名 61 岁男性因右下肢和腹部可触及紫癜及弥漫性腹痛就诊于我院。计算机断层扫描显示肠壁增厚和腹水。此外,他的血清 IgA 和尿蛋白水平升高。可触及紫癜的组织病理学发现提示血管炎,因此诊断为 IgAV。因此,开始进行类固醇治疗。逐渐地,紫癜和腹痛消失,他在入院后第 26 天出院。虽然 IgAV 在儿童中很常见,但在老年人中仅报道了少数病例。因此,当检查包括老年人在内的有可触及紫癜和腹痛的患者时,应考虑 IgAV 的可能性。

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Acute abdominal pain: Henoch-Schönlein purpura case in a young adult, a rare but important diagnosis.急性腹痛:青年成人过敏性紫癜病例,一种罕见但重要的诊断。
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Rituximab treatment for chronic steroid-dependent Henoch-Schonlein purpura: 8 cases and a review of the literature.利妥昔单抗治疗慢性类固醇依赖型过敏性紫癜:8例报告及文献复习
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Henoch-Schönlein purpura in adulthood and childhood: two different expressions of the same syndrome.成人和儿童的过敏性紫癜:同一综合征的两种不同表现形式。
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The American College of Rheumatology 1990 criteria for the classification of Henoch-Schönlein purpura.美国风湿病学会1990年亨诺-许兰紫癜分类标准。
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