Yanagi Masahiro
Muroran City General Hospital Department of Respiratory Medicine Muroran Japan.
Respirol Case Rep. 2025 May 21;13(5):e70216. doi: 10.1002/rcr2.70216. eCollection 2025 May.
A 33-year-old healthy female, employed as a hospital-based physical therapist, was exposed to a colleague diagnosed with pulmonary tuberculosis. Screening revealed a positive interferon-gamma release assay (IGRA) result. She was diagnosed with latent tuberculosis infection (LTBI) and completed a 6-month isoniazid (INH) regimen. Nine months post-treatment, she presented to the otolaryngology department with right cervical swelling and ulceration. Polymerase chain reaction (PCR) of the pus confirmed , establishing a diagnosis of cervical tuberculous lymphadenitis. She was referred to our hospital, where anti-tuberculosis therapy led to symptom resolution. Post-LTBI follow-up primarily monitors for pulmonary tuberculosis, focusing on chest abnormalities or respiratory symptoms, particularly in high-risk individuals with immunodeficiency. However, extrapulmonary tuberculosis can occur even in healthy individual's post-LTBI treatment, necessitating vigilance.
一名33岁的健康女性，受雇于一家医院担任物理治疗师，她接触了一名被诊断为肺结核的同事。筛查显示干扰素-γ释放试验（IGRA）结果呈阳性。她被诊断为潜伏性结核感染（LTBI），并完成了为期6个月的异烟肼（INH）治疗方案。治疗9个月后，她因右侧颈部肿胀和溃疡就诊于耳鼻喉科。脓液的聚合酶链反应（PCR）确诊，诊断为颈部结核性淋巴结炎。她被转诊至我院，在我院进行的抗结核治疗使症状得到缓解。LTBI治疗后的随访主要监测肺结核，重点关注胸部异常或呼吸道症状，特别是在免疫缺陷的高危个体中。然而，即使在健康个体接受LTBI治疗后，肺外结核也可能发生，因此需要保持警惕。
