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放射治疗与免疫治疗联合应用的最新进展:第八届年度免疫放射会议论文集

Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference.

作者信息

Talebi Fereshteh, Gregucci Fabiana, Ahmed Jalal, Ben Chetrit Nir, D Brown Brian, Chan Timothy A, Chand Dhan, Constanzo Julie, Demaria Sandra, I Gabrilovich Dmitry, Golden Encouse, Godkin Andrew, Guha Chandan, P Gupta Gaorav, Hasan Aisha, G Herrera Fernanda, Kaufman Howard, Li Donna, A Melcher Alan, McDonald Sierra, Merghoub Taha, Monjazeb Arta M, Paris Sébastien, Pitroda Sean, Sadanandam Anguraj, Schaue Dörthe, Santambrogio Laura, Szapary Phillippe, Sage Julien, W Welsh James, Wilkins Anna, H Young Kristina, Wennerberg Eric, Zitvogel Laurence, Galluzzi Lorenzo, Deutsch Eric, C Formenti Silvia

机构信息

Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA.

Icahn Genomics Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Oncoimmunology. 2025 Dec;14(1):2507856. doi: 10.1080/2162402X.2025.2507856. Epub 2025 May 22.

Abstract

The annual ImmunoRad Conference has established itself as a recurrent occasion to explore the possibility of combining radiation therapy (RT) and immunotherapy (IT) for clinical cancer management. Bringing together a number of preclinical and clinical leaders in the fields of radiation oncology, immuno-oncology and IT, this annual event fosters indeed essential conversations and fruitful exchanges on how to address existing challenges to expand the therapeutic value of RT-IT combinations. The 8th edition of the ImmunoRad Conference, which has been held in October 2024 at the Weill Cornell Medical College of New York City, highlighted exciting preclinical and clinical advances at the interface between RT and IT, setting the stage for extra progress toward extended benefits for patients with an increasing variety of tumor types. Here, we critically summarize the lines of investigation that have been discussed at the occasion of the 8th Annual ImmunoRad Conference.

摘要

年度免疫放疗会议已成为探讨将放射治疗(RT)和免疫治疗(IT)结合用于临床癌症管理可能性的定期活动。该年度盛会汇聚了放射肿瘤学、免疫肿瘤学和免疫治疗领域的众多临床前和临床领域的领军人物,确实促进了关于如何应对现有挑战以扩大放疗与免疫治疗联合疗法治疗价值的重要对话和富有成效的交流。第八届免疫放疗会议于2024年10月在纽约市威尔康奈尔医学院举行,会议重点介绍了放疗与免疫治疗交叉领域令人振奋的临床前和临床进展,为朝着为越来越多肿瘤类型的患者带来更多益处取得进一步进展奠定了基础。在此,我们批判性地总结了在第八届年度免疫放疗会议上讨论的研究方向。

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