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坏疽性脓皮病

Pyoderma Grangrenosum.

作者信息

Aghaei Reza, Hsu Edmund, McCoy Christopher

机构信息

Kaiser Permanente, Central Valley, Department of Emergency Medicine, Modesto, California.

University of California, Irvine, Department of Emergency Medicine, Orange, California.

出版信息

Clin Pract Cases Emerg Med. 2025 May;9(2):242-244. doi: 10.5811/cpcem.1675.

DOI:10.5811/cpcem.1675
PMID:40402053
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12097255/
Abstract

CASE PRESENTATION

We describe a middle-aged female with past medical history of ulcerative colitis presenting to the emergency department with bilateral painful ulcers rapidly growing on her lower legs in the prior four weeks. She was consulted by a dermatologist and after a thorough clinical and pathology assessment (as a diagnosis of exclusion), treatment for pyoderma gangrenosum was started.

DISCUSSION

Pyoderma gangrenosum is a painful, chronic, ulcerative disorder often occurring in association with systemic disease. We review the clinical presentation of pyoderma gangrenosum and its complications. We describe the characteristics of ulcers with pictures from the patient. Our case illustrates the findings of pyoderma gangrenosum both clinically and pathologically.

摘要

病例介绍

我们描述了一名中年女性,她有溃疡性结肠炎病史,因在过去四周内小腿上迅速出现双侧疼痛性溃疡而就诊于急诊科。皮肤科医生对她进行了会诊,经过全面的临床和病理评估(作为排除性诊断)后,开始了对坏疽性脓皮病的治疗。

讨论

坏疽性脓皮病是一种疼痛的慢性溃疡性疾病,常与全身性疾病相关。我们回顾了坏疽性脓皮病的临床表现及其并发症。我们通过患者的图片描述了溃疡的特征。我们的病例在临床和病理上都展示了坏疽性脓皮病的表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fbc/12097255/51b803546654/cpcem-9-242-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fbc/12097255/66ff012b9aa2/cpcem-9-242-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fbc/12097255/d25be1dbb059/cpcem-9-242-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fbc/12097255/51b803546654/cpcem-9-242-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fbc/12097255/66ff012b9aa2/cpcem-9-242-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fbc/12097255/d25be1dbb059/cpcem-9-242-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fbc/12097255/51b803546654/cpcem-9-242-g003.jpg

相似文献

1
Pyoderma Grangrenosum.坏疽性脓皮病
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2
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Pyoderma gangrenosum with an underlying ulcerative colitis associated with bone tuberculosis.伴有潜在溃疡性结肠炎且与骨结核相关的坏疽性脓皮病。
Indian Dermatol Online J. 2013 Jan;4(1):43-6. doi: 10.4103/2229-5178.105473.

本文引用的文献

1
Pyoderma gangrenosum - a guide to diagnosis and management .坏疽性脓皮病—诊断与治疗指南
Clin Med (Lond). 2019 May;19(3):224-228. doi: 10.7861/clinmedicine.19-3-224.
2
Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum: A Delphi Consensus of International Experts.溃疡性坏疽性脓皮病的诊断标准:国际专家德尔菲共识。
JAMA Dermatol. 2018 Apr 1;154(4):461-466. doi: 10.1001/jamadermatol.2017.5980.
3
Incidence, mortality, and disease associations of pyoderma gangrenosum in the United Kingdom: a retrospective cohort study.
英国坏疽性脓皮病的发病率、死亡率和疾病相关性:一项回顾性队列研究。
J Invest Dermatol. 2012 Sep;132(9):2166-70. doi: 10.1038/jid.2012.130. Epub 2012 Apr 26.
4
Pyoderma gangrenosum with pathergic phenomenon in pregnancy.妊娠合并具有同形反应现象的坏疽性脓皮病。
Br J Dermatol. 2000 Apr;142(4):827-8. doi: 10.1046/j.1365-2133.2000.03444.x.
5
Pyoderma gangrenosum in infants and children.婴幼儿坏疽性脓皮病
Pediatr Dermatol. 1994 Mar;11(1):10-7. doi: 10.1111/j.1525-1470.1994.tb00065.x.