Patvekar Milind A, Virmani Neha C
Department of Dermatology, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, India.
Indian Dermatol Online J. 2013 Jan;4(1):43-6. doi: 10.4103/2229-5178.105473.
Pyoderma gangrenosum is a rare noninfective neutrophilic dermatosis, characterized by progressive painful ulceration. It is frequently associated with systemic disorders like inflammatory bowel disease, rheumatoid arthritis and myeloproliferative diseases. However, its association with infectious diseases in particular with tuberculosis is extremely rare. Diagnosis is based on the history of an underlying disease, a typical clinical presentation, histopathology and exclusion of other diseases leading to ulcerations of similar appearance. Immunosuppression with corticosteroids remains the mainstay of treatment. We report a case of a 49-year-old male with long-standing ulcerative colitis, associated with tuberculosis of hip, who presented with nonhealing ulcers over the lower extremity.
坏疽性脓皮病是一种罕见的非感染性嗜中性皮病，其特征为进行性疼痛性溃疡。它常与炎症性肠病、类风湿关节炎和骨髓增殖性疾病等全身性疾病相关。然而，它与传染病尤其是与结核病的关联极为罕见。诊断基于潜在疾病史、典型临床表现、组织病理学以及排除其他导致类似外观溃疡的疾病。使用皮质类固醇进行免疫抑制仍然是主要治疗方法。我们报告一例49岁男性，患有长期溃疡性结肠炎，合并髋关节结核，下肢出现不愈合溃疡。
