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左心室辅助装置患者植入式心脏复律除颤器:当前争议

[Implantable cardioverter-defibrillators in patients with left ventricular assist devices : Current controversies].

作者信息

Linz Barbara, Pühler Thomas, Vogler Julia, Paitazoglou Christina, Tilz Roland Richard, Ensminger Stephan, Fujita Buntaro

机构信息

Klinik für Herz- und thorakale Gefäßchirurgie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, Haus A, 23538, Lübeck, Deutschland.

Klinik für Rhythmologie, Universitäres Herzzentrum Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Deutschland.

出版信息

Herzschrittmacherther Elektrophysiol. 2025 Jun;36(2):126-131. doi: 10.1007/s00399-025-01081-x. Epub 2025 May 22.

Abstract

BACKGROUND

Left ventricular assist devices (LVAD) are used to treat patients with advanced heart failure. A significant fraction of these patients simultaneously fulfill the indication for an implantable cardioverter-defibrillator (ICD).

OBJECTIVES

It is currently unclear whether patients require an ICD after LVAD implantation. In addition, it remains uncertain whether patients with an LVAD are suitable candidates for a subcutaneous ICD (S-ICD).

MATERIALS AND METHODS

The aforementioned questions were addresses using studies, case reports, and our own experience.

RESULTS

Studies have yielded varying findings on the above question. While some investigations suggest that an ICD may also be beneficial for LVAD patients, other studies highlight potential risks with limited benefit. This underscores the complexity of clinical decision-making in this specific patient cohort. S‑ICDs can suffer from significant functional impairments after LVAD implantation, making this combination controversial.

CONCLUSIONS

Due to the inconclusiveness of current studies, a general recommendation regarding the role of an ICD (both conventional and S‑ICD) after LVAD implantation cannot be established at this time. Therefore, it should involve individualized and interdisciplinary decision making.

摘要

背景

左心室辅助装置(LVAD)用于治疗晚期心力衰竭患者。这些患者中有很大一部分同时符合植入式心脏复律除颤器(ICD)的适应证。

目的

目前尚不清楚LVAD植入术后患者是否需要ICD。此外,LVAD患者是否适合皮下ICD(S-ICD)仍不确定。

材料与方法

通过研究、病例报告及我们自己的经验来解决上述问题。

结果

关于上述问题的研究结果各不相同。虽然一些调查表明ICD对LVAD患者可能也有益,但其他研究强调了潜在风险且益处有限。这凸显了这一特定患者群体临床决策的复杂性。LVAD植入后S-ICD可能会出现严重功能障碍,使得这种联合应用存在争议。

结论

由于目前研究尚无定论,此时无法就LVAD植入后ICD(传统ICD和S-ICD)的作用给出一般性建议。因此,应进行个体化和跨学科决策。

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