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Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.

作者信息

Hamilton T C, Winker M A, Louie K G, Batist G, Behrens B C, Tsuruo T, Grotzinger K R, McKoy W M, Young R C, Ozols R F

出版信息

Biochem Pharmacol. 1985 Jul 15;34(14):2583-6. doi: 10.1016/0006-2952(85)90551-9.

DOI:10.1016/0006-2952(85)90551-9
PMID:4040369
Abstract
摘要

相似文献

1
Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.丁硫氨酸亚砜胺介导的谷胱甘肽耗竭增强阿霉素、美法仑和顺铂对耐药及敏感人卵巢癌细胞系的细胞毒性。
Biochem Pharmacol. 1985 Jul 15;34(14):2583-6. doi: 10.1016/0006-2952(85)90551-9.
2
Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion.通过消耗谷胱甘肽增强美法仑对人卵巢癌细胞系的细胞毒性。
Cancer Res. 1984 Nov;44(11):5427-31.
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Cross-resistance and collateral sensitivity to natural product drugs in cisplatin-sensitive and -resistant rat lymphoma and human ovarian carcinoma cells.顺铂敏感和耐药的大鼠淋巴瘤及人卵巢癌细胞对天然产物药物的交叉耐药性和协同敏感性
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Cellular glutathione levels and sensitivity to radiation and antineoplastic agents in human ovarian cancer.人卵巢癌中的细胞谷胱甘肽水平以及对辐射和抗肿瘤药物的敏感性
Prog Clin Biol Res. 1988;276:287-93.
5
Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione.通过丁硫氨酸亚砜胺消耗谷胱甘肽增强美法仑在人卵巢癌体外模型及荷瘤裸鼠中的细胞毒性。
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Pharmacologic reversal of drug resistance in ovarian cancer.卵巢癌耐药的药理学逆转
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Depletion of a discrete nuclear glutathione pool by oxidative stress, but not by buthionine sulfoximine. Correlation with enhanced alkylating agent cytotoxicity to human melanoma cells in vitro.离散核谷胱甘肽池因氧化应激而非丁硫氨酸亚砜胺而耗竭。与体外增强的烷基化剂对人黑色素瘤细胞的细胞毒性相关。
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Characteristics of the glutathione/glutathione-S-transferase detoxification system in melphalan resistant human prostate cancer cells.美法仑耐药人前列腺癌细胞中谷胱甘肽/谷胱甘肽-S-转移酶解毒系统的特征
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Modulation of drug resistance in human ovarian cancer: experimental results and clinical applications.人类卵巢癌耐药性的调控：实验结果与临床应用
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The relationship between nuclear glutathione levels and resistance to melphalan in human ovarian tumour cells.人卵巢肿瘤细胞中核谷胱甘肽水平与美法仑耐药性之间的关系。
Biochem Pharmacol. 1991 Feb 15;41(4):647-9. doi: 10.1016/0006-2952(91)90642-i.

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