Taha Ahmed G, Hezma A M
Department of Chemistry, Faculty of Science, South Valley University, Qena, 83523, Egypt.
Spectroscopy Department, Physics Research Institute, National Research Centre, Cairo, 12622, Egypt.
BMC Chem. 2025 May 22;19(1):139. doi: 10.1186/s13065-025-01505-2.
This paper presents the synthesis and characterization of a novel chitosan-derivative polymers by using glyoxal as acrosslinker between chitosan and N-amino-9,10-dihydro-anthracene-9,10-α,β-succinamide (AS) under our conditions. The generated polymers were characterized using X-ray diffraction (XRD) and infrared spectroscopy (IR). The results indicate the successful formation of new polymer structures with unique properties. The antimicrobial activity of Chs-Gly-AS and its modified derivatives was evaluated using the cup diffusion agar method, showing enhanced inhibition against bacteria and fungi. The results demonstrate promising antimicrobial efficacy, suggesting the potential use of these polymers in antimicrobial applications.
本文介绍了在我们的条件下，通过使用乙二醛作为壳聚糖与N-氨基-9,10-二氢蒽-9,10-α,β-琥珀酰胺（AS）之间的交联剂，合成并表征一种新型壳聚糖衍生物聚合物。使用X射线衍射（XRD）和红外光谱（IR）对生成的聚合物进行了表征。结果表明成功形成了具有独特性能的新型聚合物结构。使用杯碟扩散琼脂法评估了Chs-Gly-AS及其改性衍生物的抗菌活性，结果显示对细菌和真菌的抑制作用增强。结果证明了其有前景的抗菌功效，表明这些聚合物在抗菌应用中的潜在用途。
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