Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, Tamil Nadu, India; Centre for Herbal Pharmacology and Environmental Sustainability, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, Tamil Nadu, India.
Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, Tamil Nadu, India; Centre for Herbal Pharmacology and Environmental Sustainability, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam 603103, Tamil Nadu, India.
Int J Biol Macromol. 2024 Apr;265(Pt 2):130991. doi: 10.1016/j.ijbiomac.2024.130991. Epub 2024 Mar 22.
The most prevalent carbohydrate on Earth is cellulose, a polysaccharide composed of glucose units that may be found in diverse sources, such as cell walls of wood and plants and some bacterial and algal species. The inherent availability of this versatile material provides a natural pathway for exploring and identifying novel uses. This study comprehensively analyzes cellulose and its derivatives, exploring their structural and biochemical features and assessing their wide-ranging applications in tissue fabrication, surgical dressings, and pharmaceutical delivery systems. The use of diverse cellulose particles as fundamental components gives rise to materials with distinct microstructures and characteristics, fulfilling the requirements of various biological applications. Although cellulose boasts substantial potential across various sectors, its exploration has predominantly unfolded within industrial realms, leaving the biomedical domain somewhat overlooked in its initial stages. This investigation, therefore, endeavors to shed light on the contemporary strides made in synthesizing cellulose and its derivatives. These innovative techniques give rise to distinctive attributes, presenting a treasure trove of advantages for their compelling integration into the intricate tapestry of biomedical applications.
地球上最普遍的碳水化合物是纤维素,它是一种由葡萄糖单元组成的多糖,可以在多种来源中找到,如木材和植物的细胞壁以及一些细菌和藻类物种。这种多功能材料的固有可用性为探索和识别新用途提供了一条自然途径。本研究全面分析了纤维素及其衍生物,探讨了它们的结构和生化特性,并评估了它们在组织制造、手术敷料和药物传递系统中的广泛应用。不同纤维素颗粒作为基本成分的使用产生了具有独特微观结构和特性的材料,满足了各种生物应用的要求。尽管纤维素在各个领域都具有巨大的潜力,但它的探索主要在工业领域展开,在其初始阶段,生物医学领域就有些被忽视。因此,本研究旨在阐明纤维素及其衍生物的合成方面的当代进展。这些创新技术产生了独特的属性,为其引人注目的整合到生物医学应用的复杂织锦中提供了丰富的优势。