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冷凝集素病患者急诊胃镜检查的麻醉:一例报告及文献综述

Anesthesia for Urgent Gastroscopy in Cold Agglutinin Disease: A Case Report and Literature Review.

作者信息

Zhang Addison H, Dow Cassie L, Bellamy Jack

机构信息

Anaesthesiology, Rockhampton Hospital, Rockhampton, AUS.

Medicine, University of New South Wales, Kensington, AUS.

出版信息

Cureus. 2025 May 22;17(5):e84607. doi: 10.7759/cureus.84607. eCollection 2025 May.

DOI:10.7759/cureus.84607
PMID:40405906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12096779/
Abstract

We present the case of a 76-year-old lady who underwent an emergency gastroscopy for suspected upper gastrointestinal bleeding on a background of cold agglutinin disease, a rare autoimmune haemolytic anaemia triggered by cold temperatures. Several pre-operative and intra-operative precautions were taken to minimise the risk of hypothermia. Sedation anaesthesia was used with midazolam and gradual titration of propofol with high-flow nasal cannulae to maintain oxygenation. The anaesthetic proceeded safely and without complications, and we compared our technique to the literature.

摘要

我们报告了一例76岁女性患者的病例,该患者因疑似上消化道出血接受了急诊胃镜检查,其背景是冷凝集素病,这是一种由低温引发的罕见自身免疫性溶血性贫血。术前和术中采取了多项预防措施以将体温过低的风险降至最低。使用咪达唑仑进行镇静麻醉,并通过高流量鼻导管逐步滴定丙泊酚以维持氧合。麻醉过程安全且无并发症,我们将我们的技术与文献进行了比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbe1/12096779/a7f6a0ea5665/cureus-0017-00000084607-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbe1/12096779/a7f6a0ea5665/cureus-0017-00000084607-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbe1/12096779/a7f6a0ea5665/cureus-0017-00000084607-i01.jpg

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Anesthesia for Urgent Gastroscopy in Cold Agglutinin Disease: A Case Report and Literature Review.冷凝集素病患者急诊胃镜检查的麻醉:一例报告及文献综述
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本文引用的文献

1
Perioperative Management of a Patient With Severe Cold Agglutinin Disease Undergoing Total Hip Arthroplasty With a Cemented Stem: A Case Report.严重冷凝集素病患者行骨水泥型全髋关节置换术的围手术期管理:1 例报告
A A Pract. 2022 Dec 22;16(12):e01647. doi: 10.1213/XAA.0000000000001647. eCollection 2022 Dec 1.
2
Perioperative management of a patient with severe cold agglutinin disease by using multimodal warming measures.采用多模式升温措施对重症冷凝集素病患者进行围手术期管理。
Korean J Anesthesiol. 2021 Aug;74(4):358-360. doi: 10.4097/kja.20589. Epub 2020 Dec 7.
3
Perioperative management of cold agglutinin autoimmune hemolytic anemia in an older adult undergoing radical cystectomy for bladder cancer.
一名老年膀胱癌患者行根治性膀胱切除术时冷凝集素自身免疫性溶血性贫血的围手术期管理
Urol Case Rep. 2019 Aug 13;27:100998. doi: 10.1016/j.eucr.2019.100998. eCollection 2019 Nov.
4
Cold agglutinin disease: current challenges and future prospects.冷凝集素病:当前挑战与未来展望
J Blood Med. 2019 Apr 9;10:93-103. doi: 10.2147/JBM.S177621. eCollection 2019.
5
Body temperature regulation and anesthesia.体温调节与麻醉
Handb Clin Neurol. 2018;157:635-644. doi: 10.1016/B978-0-444-64074-1.00037-9.
6
A case report of perioperative managements for a patient with gastric cancer and cold agglutinin syndrome.一例胃癌合并冷凝集素综合征患者的围手术期管理病例报告
Medicine (Baltimore). 2017 Mar;96(10):e6082. doi: 10.1097/MD.0000000000006082.
7
Cold agglutinin disease.冷凝集素病。
Blood. 2013 Aug 15;122(7):1114-21. doi: 10.1182/blood-2013-02-474437. Epub 2013 Jun 11.
8
Cold agglutinins in patients undergoing cardiac surgery requiring cardiopulmonary bypass.心脏手术并体外循环患者中的冷自身抗体。
J Thorac Cardiovasc Surg. 2013 Sep;146(3):668-80. doi: 10.1016/j.jtcvs.2013.03.009. Epub 2013 Apr 13.
9
Major colorectal surgery in a patient with cold agglutinin disease.患有冷凝集素病患者的大肠大手术。
Anaesthesia. 2006 Jun;61(6):593-6. doi: 10.1111/j.1365-2044.2006.04650.x.