Yoon T H, Paparella M M, Schachern P A, Lindgren B R
University of Minnesota Otitis Media Research Center, Minneapolis.
Ann Otol Rhinol Laryngol Suppl. 1990 Jun;148:23-7. doi: 10.1177/00034894900990s607.
Morphometric changes in the epithelium and subepithelium of the middle ear mucosa from children younger than 10 years of age were measured at the promontory in 85 temporal bones with otitis media and in 29 normal temporal bones by use of quantitative and semiquantitative methods. Comparisons of morphologic analysis in different otitis media types showed that acute inflammatory changes were usually seen in purulent otitis media with effusion and serous otitis media with effusion, and chronic inflammatory changes were more severe in mucoid otitis media with effusion and chronic otitis media. There were overlaps, however, in histopathologic findings between different types of otitis media that suggest a continuum of otitis media types, with one type of otitis media changing into another type.
采用定量和半定量方法，对85例患有中耳炎的颞骨及29例正常颞骨的岬部进行测量，以观察10岁以下儿童中耳黏膜上皮和上皮下的形态计量学变化。不同类型中耳炎的形态学分析比较显示，急性炎症变化通常见于渗出性化脓性中耳炎和渗出性浆液性中耳炎，而慢性炎症变化在渗出性黏液性中耳炎和慢性中耳炎中更为严重。然而，不同类型中耳炎的组织病理学表现存在重叠，这表明中耳炎类型具有连续性，一种类型的中耳炎可转变为另一种类型。
