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妊娠期间原发性胃癌转移瘤引起的侵袭性肠道症状:一例报告

Aggressive Intestinal Symptoms Caused by Metastatic Tumors Originating from Primary Gastric Cancer in Pregnancy: A Case Report.

作者信息

Zhao Chunlin, Ji Jingru, Lu Shenghui, Wang Fang, Yang Hailan

机构信息

Department of Obstetrics, First Hospital of Shanxi Medical University, Taiyuan, Shanxi 030000, China.

出版信息

Matern Fetal Med. 2021 Jun 8;5(1):44-46. doi: 10.1097/FM9.0000000000000111. eCollection 2023 Jan.

Abstract

Gastric carcinoma is extremely rare in pregnancy and the prognosis for this malignancy tends to be dismal. We herein describe a case of gastric cancer in pregnancy to alert clinicians to this rare possibility. A 29-year-old woman developed abdominal spastic pain and diarrhea during the 26 weeks of gestation and her condition was confusing and hard to recognize. The patient was initially misdiagnosed as enterogastritis and inflammatory intestinal obstruction and was finally confirmed by exploratory laparotomy with intestinal and peritoneum metastases. Because the disease was not detected early enough and progressed rapidly, the pregnancy was terminated by cesarean section at 30 weeks of gestation, and then followed by systemic chemotherapy, but eventually succumbed to the lethal pneumonia. Therefore, it is of great significance to alert clinicians to note this rare possibility and to consider the differential diagnosis of this disease in pregnant women with a long course of gastrointestinal symptoms that cannot be explained by pregnancy alone, and cancer should be suspected and tested with sophisticated diagnostic procedures.

摘要

胃癌在孕期极为罕见,且这种恶性肿瘤的预后往往很差。我们在此描述一例孕期胃癌病例,以提醒临床医生注意这种罕见情况。一名29岁女性在妊娠26周时出现腹部痉挛性疼痛和腹泻,其病情复杂,难以识别。该患者最初被误诊为肠胃炎和炎性肠梗阻,最终经剖腹探查确诊为伴有肠道和腹膜转移。由于疾病未被早期发现且进展迅速,妊娠在孕30周时通过剖宫产终止,随后进行全身化疗,但最终死于致命性肺炎。因此,提醒临床医生注意这种罕见情况,并考虑对有长期胃肠道症状且不能仅用妊娠解释的孕妇进行该疾病的鉴别诊断具有重要意义,应怀疑癌症并采用精密的诊断程序进行检测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9fd/12094369/7538c282a653/mfm-5-44-g001.jpg

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