Ramnani Vinita, Ramnani Sakshi, Trivedi Divya, Deo Prateek, Jain Rahul
Ophthalmology, Bansal Hospital, Bhopal, IND.
Ophthalmology, Sankara Nethralaya, Chennai, IND.
Cureus. 2025 Apr 21;17(4):e82754. doi: 10.7759/cureus.82754. eCollection 2025 Apr.
Posterior reversible encephalopathy syndrome (PRES) is a condition marked by reversible subcortical brain swelling, often accompanied by acute neurological symptoms. It is commonly associated with renal failure, blood pressure fluctuations, cytotoxic drugs, autoimmune disorders, and preeclampsia or eclampsia. We report the case of a 34-year-old female who developed sudden blurring of vision in both eyes after an episode of accelerated hypertension. Neurological imaging revealed features of PRES, and fundoscopy showed hypertensive retinopathy in both eyes. She was managed aggressively in the ICU, and her best corrected visual acuity improved after one week, with gradual resolution of the hypertensive retinopathy. PRES typically follows a benign course, with visual deficits often resolving as the underlying systemic condition improves.
后部可逆性脑病综合征(PRES)是一种以可逆性皮质下脑肿胀为特征的病症,常伴有急性神经症状。它通常与肾衰竭、血压波动、细胞毒性药物、自身免疫性疾病以及先兆子痫或子痫相关。我们报告一例34岁女性病例,该患者在一次高血压急症发作后突然出现双眼视力模糊。神经影像学检查显示有PRES的特征,眼底镜检查显示双眼有高血压性视网膜病变。她在重症监护病房接受了积极治疗,一周后最佳矫正视力有所改善,高血压性视网膜病变也逐渐消退。PRES通常病程良性,随着潜在的全身状况改善,视力缺损常常会得到缓解。