Shokri Arman, Raoofi Afshin, Shokrpoor Sara
Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Department of Pathobiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Vet Med Sci. 2025 May;11(3):e70364. doi: 10.1002/vms3.70364.
Ichthyosis (inherited congenital condition) is a heterogeneous group of skin cornification and keratinization disorders. Ichthyosis can affect animal and human and characterized by an excessive amount of superficial scale on the skin. A male Lacaune lamb was born alive from a primiparous ewe but it was unable to stand and it was in lateral recumbency and died 12 h after birth. Skin abnormalities included all over hyperkeratosis, cracking in some parts of the body like head and neck. In histopathological investigation of the cutaneous lesions, there was moderate-to-severe thickening of the stratum corneum, with a compact and laminated pattern of orthokeratotic hyperkeratosis, whereas no abnormalities were observed in the other layers of the epidermis. Ichthyosis was diagnosed on the basis of clinical and histopathological findings. In conclusion, ichthyosis in lambs can occur in different forms, but further studies and investigations are needed to accurate classification of this condition in lamb.
鱼鳞病（遗传性先天性疾病）是一组皮肤角质化和角化异常的异质性疾病。鱼鳞病可影响动物和人类，其特征是皮肤表面有过多鳞屑。一只雄性拉库内羔羊由初产母羊顺产出生，但无法站立，呈侧卧姿势，出生后12小时死亡。皮肤异常包括全身角化过度，身体某些部位如头部和颈部出现皲裂。在对皮肤病变的组织病理学检查中，角质层有中度至重度增厚，呈现致密且分层的正角化过度模式，而表皮的其他层未观察到异常。根据临床和组织病理学检查结果诊断为鱼鳞病。总之，羔羊鱼鳞病可表现为不同形式，但需要进一步研究和调查以准确分类羔羊的这种病症。
