Love G L, Harkin J C
Acta Neuropathol. 1985;67(1-2):160-2. doi: 10.1007/BF00688137.
Clearing of stromal cell nuclei were found in two of a series of nine cases of hemangioblastoma. The contents of the clear zones were often positive for lipoprotein by immunoperoxidase staining which suggested that the contents originated from the cytoplasm. Cytoplasmic invagination was not observed but is probable; some vacuoles had a "bubbly" appearance similar to the lipid-laden cytoplasm. The finding of these variations in two of nine cases suggests that cystic change in stromal cell nuclei may not be uncommon in hemangioblastomas.
在一组9例血管母细胞瘤中，有2例发现基质细胞核消失。通过免疫过氧化物酶染色发现，透明区的内容物通常对脂蛋白呈阳性，这表明其内容物源自细胞质。未观察到细胞质内陷，但有可能存在；一些空泡呈现出与富含脂质的细胞质相似的“气泡状”外观。9例中有2例出现这些变化，这表明基质细胞核的囊性改变在血管母细胞瘤中可能并不罕见。
