Stepanov P F, Sapozhnikov A G
Arkh Anat Gistol Embriol. 1985 May;88(5):50-7.
By means of common histological, histochemical and morphometrical methods age changes in the cushion-like intimal protrusions of the intraorganic arteries have been studied in 176 uteri of women at all ages that died from trauma and other diseases which do not produce any changes in the uterus. Beginning from two years of age, in the uterus segmentary artery wall certain intimal thickenings are revealed; at this age they consist of immature fibrillar and cellular elements of the connective tissue and single myocytes. At the pubertal age an intensive development of the cushion-like protrusions is observed. The amount of myocytes in them increases at the expense of migration from muscular tunic of the vessel; they arrange chaotically. Then the structure of the elastic and collagenous carcass of the protrusions becomes more complex, the myocytes in them are oriented along the course of the artery, or along the sloping spiral. During adolescence and mature age, cyclic changes in the wall structure of the uterus intraorganic arteries are observed, depending on the phase of the menstrual cycle. During the second part of the proliferative phase, certain retruction of the protrusions is observed, and at the end of the secretion phase--maximal increase in their height. The intimal protrusions are specialized structures, playing an important role in ensuring an optimal blood circulation in the uterus during ovulation and in performing menstruation. Reverse development of these structures takes place in elderly and old age.
借助普通组织学、组织化学和形态计量学方法,对176例因创伤及其他未对子宫产生任何改变的疾病死亡的各年龄段女性子宫内动脉的垫状内膜突起的年龄变化进行了研究。从两岁起,在子宫节段性动脉壁中发现了某些内膜增厚;在这个年龄段,它们由结缔组织的未成熟纤维和细胞成分以及单个肌细胞组成。在青春期,观察到垫状突起大量发育。其中肌细胞数量因从血管肌层迁移而增加;它们排列紊乱。然后,突起的弹性和胶原支架结构变得更加复杂,其中的肌细胞沿动脉走行或沿倾斜螺旋方向排列。在青春期和成年期,观察到子宫内动脉壁结构随月经周期阶段发生周期性变化。在增殖期的后半段,观察到突起有一定程度的回缩,而在分泌期末——突起高度最大增加。内膜突起是特殊结构,在排卵期间确保子宫内最佳血液循环以及月经形成过程中发挥重要作用。这些结构在老年期会出现逆向发育。