Oehler J, Jähkel M, Schmidt J
Biomed Biochim Acta. 1985;44(4):595-602.
Various behavioural patterns such as spontaneous locomotion, open-field behaviour and aggressivity undergo typical changes in socially isolated mice. Each of them shows a specific course depending on the duration of isolation. Differences in time courses and quantitative changes demonstrate that not only a general mechanism such as decreased arousal threshold is responsible for the complex alterations. It seems that many different mechanisms in the CNS underly the isolation syndrome, but the functional connections between the different alterations are unknown.
诸如自发运动、旷场行为和攻击性等各种行为模式在社会隔离的小鼠中会发生典型变化。它们中的每一种都表现出取决于隔离持续时间的特定过程。时间进程和定量变化的差异表明，不仅诸如唤醒阈值降低这样的一般机制导致了这些复杂的改变。似乎中枢神经系统中的许多不同机制是隔离综合征的基础，但不同改变之间的功能联系尚不清楚。
