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手术病例数对藏毛窦疾病复发率的影响:一项跨研究数据综合分析

Impact of surgical case load on recurrence rates in pilonidal sinus disease: a cross-study data synthesis.

作者信息

Doll Dietrich, Maak Matthias, Faurschou Ida Kaad, Hackmann Theo, von Sochaczewski Christina Oetzmann, Braun-Münker Myriam, Iesalnieks Igors, Haas Susanne

机构信息

Department of Procto-Surgery & Pilonidal Sinus, St. Marienhospital Vechta, Academic Teaching Hospital of the MHH Hannover, Vechta, Germany.

Department of Surgery, University Hospital Erlangen of the Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 12, 91054, Erlangen, Germany.

出版信息

Int J Colorectal Dis. 2025 May 23;40(1):126. doi: 10.1007/s00384-025-04883-0.

Abstract

PURPOSE

A higher surgical caseload has been associated with better outcomes in various diseases. However, this relationship has not yet been studied for Pilonidal Sinus Disease (PSD). This study aimed to examine the impact of annual PSD surgery volumes on recurrence rates (RR).

METHODS

A comparative cross-study data synthesis was conducted, including 1074 studies with 130,599 patients, focusing on PSD recurrence rates. Studies were categorized based on annual case load (ACL) into three groups: fewer than 10 operations per year (group 1), 10-30 operations per year (group 2), and 30 or more operations per year (group 3). Kaplan-Meier analyses were performed to evaluate recurrence rates, with additional stratification by study design (randomized controlled trial (RCT) or non-RCT) and surgical treatment type.

RESULTS

In randomized controlled trials (RCTs) of primary open treatment, group 1 (< 10 surgeries/year) had a 5-year recurrence rate of 23.5%, while group 2 (10-30 surgeries/year) had a rate of 12.5% (p < 0.0001). No data was available for group 3. For primary midline closure (pmc), the 5-year recurrence rates were 14.8% for group 1, 26.3% for group 2, and 12.8% for group 3. Non-RCT studies generally showed decreasing recurrence rates with higher surgical caseloads for most treatment types. However, midline closure surgery showed no significant improvement in recurrence rates with increased caseloads.

CONCLUSION

The study demonstrates that higher surgical caseloads significantly reduce PSD recurrence rates, with notable benefits observed for centers treating 30 or more patients annually. Specialization in high-volume centers may lead to improved outcomes for PSD, particularly in flap surgeries. However, midline closure surgery continues to show persistently high recurrence rates, regardless of caseload.

摘要

目的

在各种疾病中,较高的手术病例数与更好的治疗效果相关。然而,藏毛窦疾病(PSD)尚未对此关系进行研究。本研究旨在探讨年度PSD手术量对复发率(RR)的影响。

方法

进行了一项比较性交叉研究数据综合分析,纳入1074项研究中的130599例患者,重点关注PSD复发率。根据年度病例数(ACL)将研究分为三组:每年手术少于10例(第1组)、每年手术10 - 30例(第2组)和每年手术30例及以上(第3组)。采用Kaplan - Meier分析评估复发率,并按研究设计(随机对照试验(RCT)或非RCT)和手术治疗类型进行额外分层。

结果

在原发性开放治疗的随机对照试验(RCT)中,第1组(每年手术少于10例)的5年复发率为23.5%,而第2组(每年手术10 - 30例)的复发率为12.5%(p < 0.0001)。第3组无相关数据。对于原发性中线缝合(pmc),第1组的5年复发率为14.8%,第2组为26.3%,第3组为12.8%。非RCT研究通常显示,对于大多数治疗类型,随着手术病例数增加,复发率降低。然而,中线缝合手术的复发率并未随病例数增加而显著改善。

结论

该研究表明,较高的手术病例数可显著降低PSD复发率,对于每年治疗30例及以上患者的中心观察到明显益处。高手术量中心的专业化可能会改善PSD的治疗效果,尤其是在皮瓣手术中。然而,无论病例数多少,中线缝合手术的复发率持续居高不下。

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