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皮隆尼氏病发病率上升:德国 13 年间住院患者发病率增加三分之一,且存在明显的区域性差异。

Pilonidal sinus disease on the rise: a one-third incidence increase in inpatients in 13 years with substantial regional variation in Germany.

机构信息

Klinik und Poliklinik für Kinderchirurgie, Universitätsmedizin der Johannes-Gutenberg-Universität, Mainz, Germany.

Sektion Kinderchirurgie der Klinik und Poliklinik für Allgemein-, Viszeral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Bonn, Venusberg-Campus 1, D-53127, Bonn, Germany.

出版信息

Int J Colorectal Dis. 2021 Oct;36(10):2135-2145. doi: 10.1007/s00384-021-03944-4. Epub 2021 May 16.

Abstract

PURPOSE

Collective evidence from single-centre studies suggests an increasing incidence of pilonidal sinus disease in the last decades, but population-based data is scarce.

METHODS

We analysed administrative case-based principal diagnoses of pilonidal sinus disease and its surgical therapy between 2005 and 2017 in inpatients. Changes were addressed via linear regression.

RESULTS

The mean rate of inpatient episodes of pilonidal sinus disease per 100,000 men increased from 43 in 2005 to 56 in 2017. In females, the mean rate of inpatient episodes per 100,000 women rose from 14 in 2005 to 18 in 2017. In the whole population, for every case per 100,000 females, there were 3.1 cases per 100,000 males, but the numbers were highly variable between the age groups. There was considerable regional variation within Germany. Rates of inpatient episodes of pilonidal sinus disease were increasing in almost all age groups and both sexes by almost a third. Surgery was dominated by excision of pilonidal sinus without reconstructive procedures, such as flaps, whose share was around 13% of all procedures, despite recommendations of the national guidelines to prefer flap procedures.

CONCLUSION

Rates of inpatient episodes of pilonidal sinus disease in Germany rose across almost all age groups and both sexes with relevant regional variation. The underlying causative factors are unknown. Thus, patient-centred research is necessary to explore them. This should also take cases into account that are solely treated office-based in order to obtain a full-spectrum view of pilonidal sinus disease incidence rates.

摘要

目的

单中心研究的综合证据表明,过去几十年中,藏毛窦疾病的发病率不断上升,但基于人群的数据却很少。

方法

我们分析了 2005 年至 2017 年期间住院患者中藏毛窦疾病及其手术治疗的基于病例的主要诊断。通过线性回归来探讨变化。

结果

男性每 10 万人中住院治疗的藏毛窦疾病发作率从 2005 年的 43 例增加到 2017 年的 56 例。女性每 10 万人中住院治疗的藏毛窦疾病发作率从 2005 年的 14 例增加到 2017 年的 18 例。在整个人群中,每 10 万女性中有 3.1 例男性,但各年龄段的数字差异很大。德国国内存在相当大的地区差异。几乎所有年龄组和性别组的藏毛窦疾病住院发作率都增加了近三分之一。手术主要是切除藏毛窦,没有重建手术,如皮瓣,尽管国家指南建议优先采用皮瓣手术,但皮瓣手术的比例约为 13%。

结论

德国几乎所有年龄组和性别组的藏毛窦疾病住院发作率都在上升,且存在显著的地区差异。其潜在的致病因素尚不清楚。因此,有必要进行以患者为中心的研究来探索这些因素。这也应该考虑到仅在诊所接受治疗的病例,以便全面了解藏毛窦疾病的发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fb/8426302/22249d651f54/384_2021_3944_Fig1_HTML.jpg

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