[Reactivity in vitro of the leukocytes of the earthworm Eisenia foetida Sav. to several mitogenic substances].

Earthworm leukocytes were stimulated by various mitogens including LPS, PHA and Con A. Con A could stimulate leukocytes when they were cultivated in totality. After separation into sub-populations, small-non-adherent-leukocytes and large-adherent ones showed specific reactions with mitogens. Both PHA and LPS reacted with small leukocytes but LPS had no action on large adherent leukocytes.