眼型格雷夫斯病中的促甲状腺素受体刺激性免疫球蛋白
Thyroid-stimulating immunoglobulins in ophthalmic Graves' disease.
作者信息
Teng C S, Smith B R, Clayton B, Evered D C, Clark F, Hall R
出版信息
Clin Endocrinol (Oxf). 1977 Mar;6(3):207-11. doi: 10.1111/j.1365-2265.1977.tb03316.x.
Abstract
Thyroid-stimulating immunoglobulins (TSI) have been detected by receptor assay in the sera of 43% of patients with ophthalmic Graves' disease. Comparison of the receptor assay studies with thyroid function tests indicated that in several patients the antibodies detected by receptor assay were biologically inactive. In other patients, thyroid function appeared to be under TSI control with hyperthyroidism prevented by autoimmune destruction of the thyroid.
摘要
通过受体测定法在43%的Graves眼病患者血清中检测到促甲状腺素免疫球蛋白（TSI）。受体测定研究与甲状腺功能测试的比较表明，在一些患者中，通过受体测定法检测到的抗体无生物学活性。在其他患者中，甲状腺功能似乎受TSI控制，甲状腺的自身免疫性破坏可预防甲状腺功能亢进。
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