Huang Tu, Liang Jinchu, Li Chunrong, Wang Zihao
Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 611731, China.
Peking University School and Hospital of Stomatology & National Center of Stomatology, Beijing, China.
BMC Oral Health. 2025 May 23;25(1):774. doi: 10.1186/s12903-025-06168-y.
In this review, we aimed to determine the effects of dental treatment under general anesthesia on the oral health-related quality of life and dental fear of preschool children.
A comprehensive electronic search of PubMed, Embase, Scopus, and the Cochrane Library was conducted up to July 20, 2023 (updated on April 10, 2024). A manual search and evaluation of the gray literature were also performed. Clinical trials utilizing a before-and-after design to evaluate the effects of dental treatment under general anesthesia (DGA) on oral health-related quality of life (OHRQoL) and dental fear in preschool-aged children were included in this research. To assess study quality, tools specifically designed for "before-after studies without control groups" were employed to determine potential biases. Two independent investigators conducted separate evaluations of the studies' quality assessment processes. A meta-analysis was conducted via the random effects model.
In the final analysis, 13 studies employing a pre-post design were included. The meta-analysis revealed a statistically significant difference in Early Childhood Oral Health Impact Scale (ECOHIS) scores between the pre-evaluation group (n = 1365) and the post-evaluation group (n = 1344) (mean difference [MD] = 9.61, 95% CI: 6.28-12.93; P < 0.00001). However, there was no significant difference in the mean Children's Fear Survey Schedule-Dental Subscale (CFSS-DS) score between the pre-evaluation group (n = 536) and the post-evaluation group (n = 531) (MD = 5.53, 95% CI: -16.48-27.54; P = 0.62).
This study confirmed that children who received dental treatment with general anesthesia experienced improvements in their oral health-related quality of life. However, there is insufficient evidence to support the claim that dental treatment with general anesthesia can effectively alleviate dental fear in children.
Dental treatment with general anesthesia significantly improved the OHRQoL of children. However, methods to improve dental fear in children during this procedure remain to be explored.
在本综述中,我们旨在确定全身麻醉下的牙科治疗对学龄前儿童口腔健康相关生活质量和牙科恐惧的影响。
截至2023年7月20日(2024年4月10日更新),对PubMed、Embase、Scopus和Cochrane图书馆进行了全面的电子检索。还进行了灰色文献的手工检索和评估。本研究纳入了采用前后设计来评估全身麻醉下牙科治疗(DGA)对学龄前儿童口腔健康相关生活质量(OHRQoL)和牙科恐惧影响的临床试验。为评估研究质量,采用专门为“无对照组的前后研究”设计的工具来确定潜在偏差。两名独立研究者分别对研究的质量评估过程进行了评估。通过随机效应模型进行荟萃分析。
在最终分析中,纳入了13项采用前后设计的研究。荟萃分析显示,预评估组(n = 1365)和后评估组(n = 1344)的幼儿口腔健康影响量表(ECOHIS)得分存在统计学显著差异(平均差[MD] = 9.61,95%可信区间:6.28 - 12.93;P < 0.00001)。然而,预评估组(n = 536)和后评估组(n = 531)的儿童恐惧调查量表 - 牙科分量表(CFSS - DS)平均得分无显著差异(MD = 5.53,95%可信区间: - 16.48 - 27.54;P = 0.62)。
本研究证实,接受全身麻醉牙科治疗的儿童在口腔健康相关生活质量方面有所改善。然而,没有足够的证据支持全身麻醉下的牙科治疗能有效减轻儿童牙科恐惧这一说法。
全身麻醉下的牙科治疗显著改善了儿童的OHRQoL。然而,在此过程中改善儿童牙科恐惧的方法仍有待探索。