Passingham R E
Behav Neurosci. 1985 Feb;99(1):3-21. doi: 10.1037//0735-7044.99.1.3.
It is controversial whether damage to prefrontal cortex causes an impairment of memory. In this experiment, the tissue in sulcus principalis was removed in rhesus monkeys, and they were given 25 spatial locations to remember. They were poor at the task from the first. The same animals were able to indicate which of two locations they had touched if there was no delay before they were allowed to make their report. One possibility is that frontal mechanisms operate on information in working memory.
前额叶皮质受损是否会导致记忆障碍存在争议。在本实验中,切除了恒河猴的中央沟组织,然后让它们记住25个空间位置。从一开始它们在这项任务上就表现不佳。如果在允许报告之前没有延迟,这些相同的动物能够指出它们触碰过的两个位置中的哪一个。一种可能性是额叶机制作用于工作记忆中的信息。