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[Structural characteristics of DNA from the rat liver during inhibition of protein synthesis with cycloheximide].

作者信息

Fonarev A B, Shugaliĭ A V, Papina R I, Todorov I N

出版信息

Biokhimiia. 1985 Jul;50(7):1162-6.

PMID:4041495
Abstract

At cot around 20, the rat liver DNA reassociation curves were obtained 12-48 hours after injection of the animals with sublethal doses of cycloheximide. In total preparations of DNA-24 and DNA-36 at cot 0.02-0.06, the number of fast reassociating sequences was increased, on the average, by 4%. The differences in reassociation rates for individual kinetic fractions are 2.5-3-fold. The total incorporation of the label into DNA-24 preparations is sharply decreased; however, a marked distinction in the incorporation between the fractions in parameter cot was observed.

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