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关于心脏电稳定性的机制。分形假说。

On a mechanism of cardiac electrical stability. The fractal hypothesis.

作者信息

Goldberger A L, Bhargava V, West B J, Mandell A J

出版信息

Biophys J. 1985 Sep;48(3):525-8. doi: 10.1016/S0006-3495(85)83808-X.

DOI:10.1016/S0006-3495(85)83808-X
PMID:4041542
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1329366/
Abstract

Electrical activation of the ventricles via the His-Purkinje system is represented on the body surface by a waveform with a broad range of frequency components. We speculate that this process is mediated by current flow through a fractal-like conduction network and therefore that the broadband spectrum of the depolarization waveform should be scaled as a power-law distribution. The prediction is confirmed by Fourier analysis of electrocardiographic data from healthy men. This observation suggests a new dynamical link between nonlinear (fractal) structure and nonlinear function in a stable physiologic system.

摘要

通过希氏-浦肯野系统对心室进行电激活,在体表由一个具有广泛频率成分的波形表示。我们推测,这一过程是由电流通过类似分形的传导网络介导的,因此去极化波形的宽带频谱应以幂律分布进行缩放。对健康男性心电图数据的傅里叶分析证实了这一预测。这一观察结果表明,在一个稳定的生理系统中,非线性(分形)结构与非线性功能之间存在一种新的动态联系。

相似文献

1
On a mechanism of cardiac electrical stability. The fractal hypothesis.关于心脏电稳定性的机制。分形假说。
Biophys J. 1985 Sep;48(3):525-8. doi: 10.1016/S0006-3495(85)83808-X.
2
Is the power spectrum of the QRS complex related to a fractal His-Purkinje system?QRS波群的功率谱与分形的希氏-浦肯野系统有关吗?
Am J Cardiol. 1993 Feb 15;71(5):430-3. doi: 10.1016/0002-9149(93)90446-j.
3
Fractal system--a time domain approach.分形系统——一种时域方法。
Ann Biomed Eng. 1990;18(6):597-621. doi: 10.1007/BF02368450.
4
The vagus and the ventricles.迷走神经与心室。
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5
1/f alpha power spectrum of the QRS complex does not imply fractal activation of the ventricles.QRS波群的1/fα功率谱并不意味着心室的分形激活。
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6
Statistically compensated averaging method for noninvasive recording of his-purkinje activity.用于无创记录希氏-浦肯野系统活动的统计补偿平均法。
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7
Multichannel signal processing based on logic averaging.基于逻辑平均的多通道信号处理
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Biomed Tech (Berl). 1988 Oct;33(10):224-30.

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Why Ablation of Sites With Purkinje Activation Is Antiarrhythmic: The Interplay Between Fast Activation and Arrhythmogenesis.为何消融浦肯野纤维激动部位具有抗心律失常作用:快速激动与心律失常发生之间的相互作用。
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The fractal-like complexity of heart rate variability beyond neurotransmitters and autonomic receptors: signaling intrinsic to sinoatrial node pacemaker cells.心率变异性超出神经递质和自主受体的类分形复杂性:窦房结起搏细胞固有的信号传导
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Synchronization of sinoatrial node pacemaker cell clocks and its autonomic modulation impart complexity to heart beating intervals.窦房结起搏细胞时钟的同步及其自主调节使心跳间期变得复杂。
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Intracardiac origin of heart rate variability, pacemaker funny current and their possible association with critical illness.心率变异性的心脏内起源、起搏电流及其与危重病的可能关联。
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1/f Power spectral density of the cardiac QRS complex is not associated with a fractal Purkinje system.心脏QRS复合波的1/f功率谱密度与分形浦肯野系统无关。
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