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撤稿声明:源自过表达SDF1的间充质干细胞的外泌体抑制心肌梗死小鼠缺血心肌细胞凋亡并促进心脏内皮微血管再生

RETRACTION: Exosomes Derived From SDF1-Overexpressing Mesenchymal Stem Cells Inhibit Ischemic Myocardial Cell Apoptosis and Promote Cardiac Endothelial Microvascular Regeneration in Mice With Myocardial Infarction.

出版信息

J Cell Physiol. 2025 Jul;240(7):e70076. doi: 10.1002/jcp.70076.

Abstract

X.-H. Gong, H. Liu, S.-J. Wang, S.-W. Liang, and G.-G. Wang, "Exosomes Derived From SDF1-Overexpressing Mesenchymal Stem Cells Inhibit Ischemic Myocardial Cell Apoptosis and Promote Cardiac Endothelial Microvascular Regeneration in Mice With Myocardial Infarction." Journal of Cellular Physiology 234, no. 8 (2019): 13878-13893. https://doi.org/10.1002/jcp.28070. The above article, published online on February 5, 2019, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor-in-Chief, Robert Heath, and Wiley Periodicals LLC. A third party shared a report from the National Natural Science Foundation of China, which indicated that data in this article had been purchased from an external company (National Natural Science Foundation of China 2015). An investigation by the publisher found that this fact is not reported in the article and also that the article is missing necessary information on the ethical approval for animal and human experiments performed as part of this study. The authors responded to an inquiry by the publisher requesting original data and evidence of approval for animal and human experiments. The authors stated that they conducted partial pre-experiments and then commissioned third-party companies to conduct the main experiments. The authors further stated that those companies could not provide raw data. The authors did not provide information regarding ethical approval for the animal and human experiments reported in the article. The authors requested the withdrawal of their article. The retraction has been agreed to because the data and ethical approval of experiments reported in this article cannot be validated.

摘要

龚晓华、刘浩、王淑娟、梁世伟、王贵刚,“源自过表达SDF1的间充质干细胞的外泌体抑制缺血心肌细胞凋亡并促进心肌梗死小鼠心脏内皮微血管再生”。《细胞生理学杂志》234卷,第8期(2019年):13878 - 13893页。https://doi.org/10.1002/jcp.28070 。上述文章于2019年2月5日在线发表于威利在线图书馆(wileyonlinelibrary.com),已根据作者、期刊主编罗伯特·希思以及威利期刊有限责任公司的协议撤回。第三方分享了中国国家自然科学基金的一份报告,该报告表明本文中的数据是从一家外部公司购买的(中国国家自然科学基金2015年)。出版商的调查发现,本文未报告这一事实,并且本文缺少作为本研究一部分进行的动物和人体实验的伦理批准的必要信息。作者回应了出版商要求提供原始数据以及动物和人体实验批准证据的询问。作者表示他们进行了部分预实验,然后委托第三方公司进行主要实验。作者进一步表示,那些公司无法提供原始数据。作者未提供本文中报告的动物和人体实验伦理批准的信息。作者要求撤回他们的文章。由于本文中报告的实验数据和伦理批准无法得到验证,因此同意撤回。

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