Savel'ev V S, Chekareva I A, Mishnev O D, Bogdanov O A
Biull Eksp Biol Med. 1985 Sep;100(9):351-5.
The canine ischemic muscle tissue was subjected to a comprehensive morphological study after the recovery of the blood flow in the limbs for 2 hours. The effectiveness of of the recovery of the blood flow after the 3-hour ischemia was supported in acute experimental occlusion of the artery. The blood flow recovery after 6 hours of ischemia was associated with appreciable structural and metabolic abnormalities in the skeletal muscle fibers. These abnormalities were more demonstrable during recirculation after 9 and 12 hours of ischemia. No morphological criteria that might indicate whether the ischemic damage to the skeletal muscle is reversible or irreversible were defined. A comprehensive morphological study with an assay of structural and metabolic alterations is required instead.
在肢体血流恢复2小时后，对犬缺血肌肉组织进行了全面的形态学研究。在急性实验性动脉闭塞中，3小时缺血后血流恢复的有效性得到了证实。缺血6小时后的血流恢复与骨骼肌纤维中明显的结构和代谢异常有关。这些异常在缺血9小时和12小时后的再灌注过程中更为明显。未定义可能表明骨骼肌缺血损伤是可逆还是不可逆的形态学标准。相反，需要进行一项综合形态学研究，并对结构和代谢改变进行分析。
