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一例小儿下颌骨纤维发育不良的误诊

Misdiagnosis of a Paediatric Fibrous Dysplasia of the Mandible.

作者信息

Alawadhi Retaj, Alsairefi Sood, AlMutairi Mishal M

机构信息

Medicine and Surgery, Royal College of Surgeons in Ireland, Dublin, IRL.

General Surgery, Royal College of Surgeons in Ireland, Dublin, IRL.

出版信息

Cureus. 2025 Apr 23;17(4):e82872. doi: 10.7759/cureus.82872. eCollection 2025 Apr.

DOI:10.7759/cureus.82872
PMID:40416291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12102579/
Abstract

Fibrous dysplasia (FD) is a chronic benign bone lesion, mainly affecting young individuals, that could be monostotic or polyostotic in nature leading to the replacement of normal bone with the excess proliferation of fibrous tissue. Patients are usually asymptomatic and are incidentally diagnosed after an oral imaging. The first symptom is typically the painless growth of the affected bone, presenting as facial asymmetry. Here, we present a case of an 18-year-old female patient with a recent diagnosis of right mandibular fibrous dysplasia who was misdiagnosed for the past seven years. The physical examination indicated the presence of hard right submandibular swelling, and imaging confirmed fibrous dysplasia of the right mandible with involvement of the right alveolar foramen and oedematous changes of the right masseter muscle. This case highlights the familiarity of fibrous dysplasia of the mandible in young patients and emphasizes the importance of careful investigation measures and multidisciplinary collaboration in achieving correct diagnosis and management for such challenging cases.

摘要

骨纤维异常增殖症(FD)是一种慢性良性骨病变,主要影响年轻人,本质上可为单骨型或多骨型,导致正常骨被纤维组织过度增殖所替代。患者通常无症状,在口腔影像学检查后偶然被诊断。首发症状通常是受累骨的无痛性生长,表现为面部不对称。在此,我们报告一例18岁女性患者,近期诊断为右下颌骨纤维异常增殖症,过去七年一直被误诊。体格检查发现右侧下颌下硬性肿胀,影像学检查证实右下颌骨纤维异常增殖症,累及右牙槽孔,右侧咬肌有水肿改变。该病例凸显了年轻患者下颌骨纤维异常增殖症的常见性,并强调了在处理此类具有挑战性的病例时,仔细的检查措施和多学科协作对于实现正确诊断和管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbc/12102579/e143c4ee357b/cureus-0017-00000082872-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbc/12102579/903df457c0d0/cureus-0017-00000082872-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbc/12102579/e143c4ee357b/cureus-0017-00000082872-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbc/12102579/903df457c0d0/cureus-0017-00000082872-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbc/12102579/e143c4ee357b/cureus-0017-00000082872-i02.jpg

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本文引用的文献

1
Incidence and Prevalence of Fibrous Dysplasia/McCune-Albright Syndrome: A Nationwide Registry-Based Study in Denmark.纤维结构不良/ McCune-Albright 综合征的发病率和患病率:丹麦全国基于登记的研究。
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Int J Mol Sci. 2023 Oct 26;24(21):15591. doi: 10.3390/ijms242115591.
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颌骨纤维异常增殖症:影像学与治疗进展
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